184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.
86 citations
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January 1990 in “The Journal of Pediatrics” This study suggests that biotin therapy may be beneficial for individuals with partial biotinidase deficiency, as some developed symptoms later, which resolved with treatment.
67 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses telogen effluvium, a common type of hair loss, focusing on differentiation from other conditions and potential causes, but presents no new research findings.
59 citations
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July 2015 in “Journal of Immunology” This study found that disrupting inflammasome signaling by eliminating caspase-1 and -11 in mice reduced skin inflammation and delayed the onset of disease, highlighting their role in skin disease pathogenesis.
55 citations
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July 1983 in “Journal of the American Academy of Dermatology” This case study of three siblings highlights the importance of recognizing dermatologic signs—alopecia and periorificial dermatitis—for early diagnosis and treatment of biotin-responsive multiple carboxylase deficiency.
41 citations
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January 2000 in “Hormone Research in Paediatrics” In this case study, a 55-year-old woman with androgenetic alopecia was ultimately diagnosed with hepatic cortisone reductase deficiency after initially suspected 21-hydroxylase deficiency was ruled out.
33 citations
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September 2017 in “Journal of clinical immunology” This review summarizes recent findings on FOXN1's essential role in thymus and skin biology and discusses emerging therapeutic approaches for immune disorders with athymia, but reports no new clinical results.
32 citations
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December 1969 in “The Lancet” This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.
28 citations
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November 2013 in “The FASEB journal” In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.
27 citations
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January 2016 in “Cellular Physiology and Biochemistry” This study found that the extract of Bidens pilosa L. improved dry eye symptoms associated with androgen deficiency in rats by enhancing tear production, stabilizing the tear film, and reducing lacrimal gland inflammation.
20 citations
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February 2018 in “Journal of the European Academy of Dermatology and Venereology” This study reported that applying a cream with 5% vitamin C reduced dermatoporosis-related purpura, suggesting the condition may be linked to vitamin C deficiency.
20 citations
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June 2010 in “Dermatology Online Journal” This report describes a case of hypozincemia type-II in an exclusively breast-fed infant, which resolved with zinc therapy and weaning, highlighting genetic factors in zinc transporter gene SLC30A2.
18 citations
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June 2016 in “Clinical and Experimental Dermatology” This case study reports that an infant with maple syrup urine disease developed acrodermatitis dysmetabolica due to low isoleucine levels, and increasing the isoleucine dose improved the condition.
18 citations
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January 1987 in “PubMed” This study found that plasma zinc concentrations were significantly lower in patients with alcoholic cirrhosis, especially those with skin manifestations of zinc deficiency, compared to control subjects.
14 citations
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November 2015 in “Annals of the New York Academy of Sciences” This review discusses dietary manipulation strategies in a mouse model of CBS deficiency and reports no new results; the authors emphasize the importance of understanding gene-diet interactions.
13 citations
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August 1982 in “PubMed” This article reviews zinc deficiency disorders, highlighting their clinical features and treatment with zinc therapy, but reports no new clinical results.
10 citations
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April 2020 in “Clinics in Dermatology” This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.
5 citations
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August 2018 in “International Journal of Dermatology” This study suggests obstructive sleep apnea may increase the risk of male-pattern baldness in men with a family history of hair loss, and links low serum transferrin saturation levels to both conditions.
4 citations
,
July 2019 in “Clinical and experimental dermatology” This abstract does not provide specific study results or findings, but it notes that the publisher is not responsible for the supplemental content's accuracy and functionality, directing any queries to the article's corresponding author.
3 citations
,
December 1968 in “PubMed” This letter reports that serum iron levels and binding capacities were normal in women with androgenetic alopecia, suggesting that the condition may not be related to iron deficiency.
2 citations
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July 2025 in “BMC Women s Health” This study confirms that many iron deficiency symptoms occur in non-anemic women, with transferrin saturation showing a strong correlation with symptom diversity, suggesting its potential as an early diagnostic biomarker.
2 citations
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July 2022 in “Dermatology practical & conceptual” In this study, researchers found that women with telogen effluvium had lower MCV/RDW ratios, MPV, and ferritin levels compared to healthy controls, suggesting iron deficiency's involvement in this chronic hair loss condition.
2 citations
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March 2020 in “PubMed” This study found no significant difference in serum biotin levels between patients with telogen effluvium and control subjects.
2 citations
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January 2011 This study found that zinc levels were significantly decreased in both alopecia areata and vitiligo patients compared to controls, suggesting zinc may play an important role in the etiopathogenesis of these conditions.
1 citations
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May 2025 in “The Journal of Phytopharmacology” This review identifies natural plants that possess androgen-related compounds, highlighting the potential of phytoandrogens as alternatives to allopathic treatments for conditions like hypogonadism, impotence, infertility, and erectile dysfunction.
1 citations
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January 2025 in “Pediatria i Medycyna Rodzinna” This case report of a 16-month-old girl with acrodermatitis enteropathica, who showed atypical symptoms and normal zinc serum levels, highlights how genetic testing and zinc supplementation led to marked improvement in her condition, underscoring the importance of accurate diagnosis in metabolic disorders.
1 citations
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July 2024 in “International Journal of Innovative Science and Research Technology (IJISRT)” In this case report, a 36-year-old woman was diagnosed with iatrogenic Cushing Syndrome caused by topical steroid use, leading to skin ulcers, diabetes, and anemia. Her condition improved after discontinuing the steroids and receiving appropriate treatment.
1 citations
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January 2002 in “Journal of Clinical Dermatology” This study found that women with chronic telogen effluvium had significantly lower serum ferritin levels and higher TIBC levels compared to normal females, suggesting a potential role for iron stores in the condition's pathogenesis.
Nutrition plays a key role in managing skin disorders, with specific dietary changes helping improve conditions like acne, dermatitis, psoriasis, alopecia, and skin cancer.
January 2026 in “University of Science and Technology Institutional Repository (University of Science and Technology, Sana’a, Yemen)” This study found that adult males in Taiz, Yemen with dermatological disorders had significantly lower serum zinc and hemoglobin levels compared to healthy controls, highlighting the importance of assessing micronutrient status in skin disease management.