51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” This review examines androgen replacement therapy in women for treating androgen deficiency symptoms and reports no new clinical results, while noting potential safety within a specific dose range.
50 citations
,
March 1992 in “PubMed” This review discusses the clinical manifestations of malnutrition in children, particularly highlighting the overlapping skin changes from various nutrient deficiencies, and reports no new clinical results.
40 citations
,
September 2019 in “World journal of clinical cases” In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.
37 citations
,
May 2016 in “Deutsches Arzteblatt International” This review outlines various causes and manifestations of hair loss, highlighting that each type has distinct underlying mechanisms and requires specific treatment approaches, without reporting new clinical results.
36 citations
,
January 2012 in “International Journal of Trichology” This review discusses madarosis, its diverse causes, and suggests follicular unit transplantation as a useful treatment for scarring types, but reports no new clinical results.
32 citations
,
October 2005 in “PubMed” This case study describes a 59-year-old man with scurvy, initially misdiagnosed as leukocytoclastic vasculitis, who showed rapid improvement after vitamin C supplementation; it reviews scurvy's biochemical basis, symptoms, and management.
30 citations
,
September 2017 in “Clinics in Dermatology” This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.
25 citations
,
January 1992 in “International Journal of PIXE” This review discusses medical conditions and therapies related to various elements, such as zinc, copper, mercury, cadmium, lead, chromium, and arsenic, without reporting new experimental results; it highlights past findings on deficiencies, toxicities, and historical cases.
22 citations
,
December 1992 in “The journal of pediatrics/The Journal of pediatrics” This study reported that oral zinc therapy improved hair and skin abnormalities in patients with dry brittle hair, alopecia, and other symptoms, regardless of demonstrated zinc deficiency.
18 citations
,
April 2013 in “Inflammatory Bowel Diseases” This review discusses the various potential causes of hair loss in patients with inflammatory bowel disease, including telogen effluvium from disease flares, but provides no prevalence data; the authors outline a practical assessment and management approach.
16 citations
,
October 1996 in “PubMed” This study concluded that hormonal replacement therapy can improve skin ageing symptoms by increasing skin thickness and alleviating dryness and hyposeborrhoea in postmenopausal women.
14 citations
,
January 2019 in “PubMed” This review examines the potential roles of vitamin D in the pathogenesis of alopecia areata and suggests that vitamin D analogs like calcipotriol may have therapeutic potential.
14 citations
,
December 2010 in “Dermatologica Sinica” This article reviews recent advances and therapeutic approaches in treating alopecia areata, highlighting new potential treatments like pulse corticosteroid therapy, but reports no new research findings.
11 citations
,
January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
10 citations
,
August 2012 in “Current Problems in Pediatric and Adolescent Health Care” This review explores hair signs related to nutrition disorders, such as thin and dyspigmented hair, without presenting new clinical findings; the authors highlight unknowns regarding underlying causes.
9 citations
,
February 1984 in “Zentralblatt für Veterinärmedizin Reihe A” This study found that feeding piglets high levels of egg white led to severe biotin deficiency, causing hair loss and brittle claws, highlighting biotin's role in maintaining healthy skin and claws.
8 citations
,
July 2022 in “International Journal of Molecular Sciences” This study found that in estrogen receptor-positive breast cancer cells, 17β-estradiol repressed polyamine oxidase transcription by interacting with AP-1 sites on its promoter.
6 citations
,
April 2019 in “Nutrients” This study found that biotin deficiency in mice led to reduced zinc levels, disappearance of epidermal Langerhans cells, and increased ATP production, resulting in prolonged irritant contact dermatitis.
6 citations
,
January 2019 in “International Journal of Medicine in Developing Countries” This study found that premature greying of hair was reported in 42.5% of young adults from King Faisal University, with higher prevalence among females, and noted associations with various health and lifestyle factors.
6 citations
,
August 2008 in “Journal of Paediatrics and Child Health” This case report describes a 5-year-old girl whose undiagnosed Coeliac disease presented with symptoms of alopecia, iron deficiency anemia, and trichobezoar, indicating a link between malabsorption, anemia, and resulting pica.
5 citations
,
March 2020 in “Current Opinion in Endocrine and Metabolic Research” This review discusses the contribution of non-androgen causes to acne and female pattern hair loss in PCOS and emphasizes the need for targeted treatment approaches without relying on hyperandrogenism as a diagnostic marker.
5 citations
,
October 2019 in “Giornale italiano di dermatologia e venereologia” This review highlights the potential benefits of biotin in treating skin disorders related to biotin deficiency but reports no new clinical results.
5 citations
,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.
5 citations
,
July 2014 in “Journal of X-Ray Science and Technology” This study suggests that hair analysis could serve as a diagnostic tool for detecting calcium channel activity, which influences hair calcium levels and may indicate calcium deficiency or related disease states.
5 citations
,
December 1978 in “PubMed” This article reviews the connection between malabsorption syndrome and skin diseases, reporting common skin complications and noting their improvement with malabsorption treatment; it offers no new clinical results.
4 citations
,
May 2022 in “Medicina” In this study, Kampo medicine was frequently prescribed for general fatigue in long COVID, particularly the formula hochuekkito, suggesting its potential as a treatment option.
4 citations
,
July 2012 in “Dermatologic Clinics” This article reviews advances in the histologic evaluation of alopecia and hair-related disorders, without presenting new clinical results.
4 citations
,
November 2009 in “Medical Clinics of North America” This article discusses how changes in hair and nails may indicate systemic diseases, but it provides no new results; the authors emphasize their usefulness in clinical diagnosis.
3 citations
,
November 2021 in “Applied Microscopy” This article presents a comprehensive overview of hair microscopy techniques and their diagnostic potential for systemic and cutaneous disorders, emphasizing its usefulness in resource-limited settings and highlighting the underutilization of this non-invasive method due to lack of awareness.
3 citations
,
June 2020 in “Cutis” This review discusses the link between nutritional deficiencies and cutaneous diseases, outlining risk factors, disease presentations, diagnostic processes, and supplementation in undernourished patients, but reports no new results.