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This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.

In this study, researchers discovered that fat grafting helps reduce dermal fibrosis in radiation-injured mouse skin by decreasing specific fibroblast subpopulations associated with Fra/c-Jun signaling.

In this case report, a 24-year-old male with a translucent nodule in the left nasolabial fold was diagnosed with a solitary fibrofolliculoma with cystic changes upon histopathology, emphasizing the rarity and potential for misdiagnosis of these benign cutaneous tumors.

This article reviews central centrifugal cicatricial alopecia, including its various forms and potential multifactorial causes, but provides no new clinical findings.

This case report describes a 59-year-old woman with cicatricial alopecia and multiple skin lesions, including nodules and plaques, with biopsy results showing a lymphocytic infiltrate and collagen replacement.

This report describes early and late stages of central centrifugal cicatricial alopecia in two Black women, highlighting progression from a small to a large central patch of hair loss.

This study found that crosstalk between fibroblasts and endothelial cells significantly contributes to hypertrophic scar formation by enhancing fibroblast activity through cytokine secretion, with pathway analyses suggesting molecular targets for potential therapeutic interventions.

This study reports that in systemic sclerosis, CD34+ dermal fibroblasts transition to CD34−, podoplanin+, and CD90+ fibroblasts across the dermis, suggesting a role in unchecked fibrosis.

This study reported that connective tissue nevi show distinctive dermoscopic and RCM features, with RCM being particularly helpful for diagnosing lesions of less than one year in duration.

This study provides a comprehensive framework for understanding, managing, and addressing skin fibrosis, highlighting common pathways and new therapeutic opportunities for various fibrosis-related disorders that currently lack effective treatments.

This review discusses recent findings on fibrotic lipodystrophy, highlighting the critical roles of lipid-filled cells in tissue function and their loss during fibrogenesis, with implications for fibrosis in tissues like skin, lung, and liver.

In this study, researchers found histopathological similarities between L-tryptophan eosinophilic myalgia syndrome and idiopathic eosinophilic fasciitis, with certain unique inflammatory features present in the former.

This case report describes a 54-year-old man diagnosed with fibrosing alopecia in a pattern distribution, presenting with follicular inflammatory lesions and scleroatrophy on the scalp.

This study found that WISP-1 plays a key role in ligamentum flavum fibrosis through the Hedgehog-Gli1 pathway, with cyclopamine showing potential to reduce fibrosis effects in a rabbit model.

This article discusses features, genetics, and diagnostic challenges of central centrifugal cicatricial alopecia in African American women but reports no new clinical results.

Mast cells may significantly contribute to central centrifugal cicatricial alopecia.

This study reports the first known case of multiple type nevus lipomatosus cutaneous superficialis in a 10-month-old girl, with the unique feature of perifollicular fibrosis.

This case report suggests that in African-American patients, the histology of Central Centrifugal Cicatricial Alopecia may resemble lichen planopilaris, indicating a potential diagnostic challenge.

In this study, electron microscopy of follicular mucinosis showed severe cytoplasmic degeneration in hair follicles, with myelin figures and onion-like lamellar structures, but no indications of mucin release through degeneration or degradation were found.

This study found that a pro-fibrotic Wnt1/βcatenin injury response is crucial for maintaining cardiac function following acute ischaemic cardiac injury by activating the epicardium and cardiac fibroblasts.

This review explores the diverse roles and heterogeneity of fibroblasts across different organs, highlighting their potential involvement in both normal tissue functioning and fibrotic diseases, but reports no new experimental results.

This study found poor agreement among dermatopathologists in identifying and grading fibrosis in traction alopecia, suggesting the need for better diagnostic methods for early fibrosis detection.

This case report details a 36-year-old man with atypical necrobiosis lipoidica on his face, characterized by annular lesions and prominent giant cells without clear granuloma formation.

EF and PXE not closely related.

This review discusses the role of perifollicular fibrosis in androgenetic alopecia and suggests that targeting specific signaling pathways could improve treatment outcomes, but reports no new clinical results.

The document concludes that using gadolinium-based contrast agents during MRI can be linked to Nephrogenic Systemic Fibrosis in patients with severe kidney disease.

In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.

This study developed a validated murine model of hypertrophic scar contraction, demonstrating similarities to human skin and observing graft contraction and tissue characteristics over time.

This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.

In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.