research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
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research Computational Screening of Repurposed Drugs and Natural Products Against SARS-CoV-2 Main Protease as Potential COVID-19 Therapies
Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.
research Cloning, Computational Analysis and Expression Profiling of Steroid 5 Alpha-Reductase 1 (SRD5A1) Gene During Reproductive Phases and Ovatide Stimulation in Endangered Catfish, Clarias Magur
The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
research Identification of Neprilysin as a Potential Target of Arteannuin Using Computational Drug Repositioning
Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
research In-Silico Studies in Herbal Drugs: A Review
Computational methods can speed up and improve the development and safety of herbal drugs.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Foundations of Bayesian Networks
Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.
research The Hair Follicle Enigma
The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
research Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias
The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
research Scarring Alopecias: Pathology and an Update on Digital Developments
New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.
research Sparse Haplotype-Based Fine-Scale Local Ancestry Inference at Scale Reveals Recent Selection on Immune Responses
Recent selection on immune response genes was identified across seven ethnicities.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models
Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
research Exploring the Effects of Wetting and Free Fatty Acid Deposition on a Hair Fiber Surface Model Incorporating Keratin Associated Protein 5-1
Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.
research Caffeine Docking Studies with Keratin: Implications for Its Cosmetic Applications
Caffeine may be good for hair growth and skin care because it binds well with keratin.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Stem Cells, Organoids and Their Applications for Human Diseases: Special Issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer
Human hair keratin might be good for filtering out harmful substances from water.
research In Silico Characterization and Analysis of Clinically Significant Variants of Lipase-H (LIPH Gene) Protein Associated with Hypotrichosis
Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
research Selection Signatures for Fiber Production in Commercial Species: A Review
Genomic research can help improve the quality and production of natural fibers in animals.
research Challenges Associated With the Identification of Germline Variants on Myeloid Malignancy Genomic Profiling—A Singaporean Experience
Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
research Transforming 300 Billion Points of Data into Diagnostics, Therapeutics, and New Insights into Disease
Large data can lead to new medical discoveries and personalized medicine.
research Trichoscopy of Alopecia Areata: Hair Loss Feature Extraction and Computation Using Grid Line Selection and Eigenvalue
Researchers developed an algorithm for self-diagnosing scalp conditions with high accuracy using smart device-attached microscopes.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Scalp Disease Analysis Using Deep Learning Models
Deep learning models can analyze scalp diseases effectively.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.