4 citations
,
September 2012 in “Transplant international” Graft rejection in a hand transplant may trigger hair loss due to autoimmune responses.
January 2023 in “Journal of Plastic Surgery and Hand Surgery” This study observed that both autogenic and xenogenic PRP improved graft viability in rabbits compared to control, with autogenic PRP showing better histopathological results.
50 citations
,
December 2007 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” In this study, the combination of keratin-gelatin from poultry feathers promoted early acceptance and viability of full-thickness skin mesh grafts in experimental dogs compared to other treatments.
10 citations
,
December 1999 in “Journal of The American Academy of Dermatology” This case report describes how a combined nude and hair-bearing full-thickness skin graft was used after micrographic surgery to achieve a cosmetically satisfactory reconstruction of a large eyebrow defect.
51 citations
,
August 2013 in “Journal of Investigative Dermatology” This study demonstrated that cultured human dermal papilla cells can induce full hair follicle formation when combined with neonatal foreskin keratinocytes in a grafted dermal-epidermal construct on mice.
May 2025 in “Wound Repair and Regeneration” This study found that the peptide TSN6 increased epidermal thickness and promoted hair follicle formation in dermal–epidermal composites grafted onto nude mice, with TSN6-treated composites showing more hair follicles and retained grafts compared to control groups.
1 citations
,
September 2024 in “Journal of Education Health and Sport” This review evaluates the clinical use of composite dermal-epidermal skin substitutes, with a focus on advancements such as the "BioMask" for facial skin trauma, highlighting the potential of 3D bioprinting and bioengineered skin in improving wound treatment and reconstruction.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
January 2007 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” This study concluded that keratin-gelatin composite films were more effective than bFGF-gelatin films in promoting early and uncomplicated wound healing in dogs, observing improved epithelialization and graft acceptance.
This study found that keratin-gelatin composite films effectively promoted early wound healing and full-thickness skin graft acceptance in dogs, outperforming bFGF-gelatin films.
9 citations
,
May 2012 in “Journal of Craniofacial Surgery” This study reports that reconstructing perioral soft tissue defects with submental tissue resulted in satisfactory aesthetic outcomes and minimal donor-site morbidity.
1 citations
,
January 2010 in “Elsevier eBooks” The document concludes that local flaps are effective for reconstructive surgery in the head and neck, offering good skin match and function.
4 citations
,
January 2009 in “Indian Journal of Plastic Surgery” This study observed that good surgical outcomes for secondary cicatricial alopecia were achieved in 18 patients, with method selection influenced by the size, location, and shape of alopecia.
This article reviews surgical techniques for addressing scalp defects and highlights hair restoration as a cosmetic improvement strategy, but it reports no new clinical results.
January 2009 in “Indian Journal of Plastic Surgery” This study evaluated surgical methods for treating cicatricial alopecia and found that factors such as size, location, and shape are crucial in deciding the approach, with good outcomes seen in 18 out of 24 patients.
34 citations
,
October 2004 in “Plastic and Reconstructive Surgery” In this study, composite grafts were effectively used for reconstructing lower third nasal defects, providing good aesthetic outcomes with minimal complications and avoiding long scars associated with larger flaps.
32 citations
,
May 2023 in “Frontiers in Immunology” This review explores the cellular dynamics of graft rejection in vascularized composite allotransplantation and discusses how understanding these processes might lead to innovative treatments for managing rejection.
68 citations
,
August 2014 in “Stem Cells Translational Medicine” This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.
July 2024 in “Journal of Investigative Dermatology” A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.
18 citations
,
March 2018 in “Archives of Plastic Surgery” This article reviews the use of superficial temporal artery island flaps for facial reconstruction and provides a systematic approach for managing composite facial defects, reporting no major complications in 72 patients.
15 citations
,
April 2014 in “Experimental Dermatology” This study observed that earlier-passage keratinocyte cultures led to superior hair follicle neogenesis in dermal-epidermal composites grafted onto immunodeficient mice, suggesting their potential utility in studying human hair follicle development.
89 citations
,
January 2021 in “Molecules” This review discusses the applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing, but reports no new experimental results, highlighting the need for further development and analysis.
34 citations
,
July 2022 in “Gels” This review explores the potential of alginate as a promising alternative to donor tissue for corneal transplantation due to its adaptability, transparency, and low immunogenicity, and discusses how chemical modifications can enhance its properties for use in corneal tissue engineering.
43 citations
,
July 2019 in “Stem Cells International” This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
March 2018 in “John Wiley & Sons, Ltd eBooks” This chapter reviews classification and techniques of surgical therapies for treating stable, recalcitrant vitiligo, highlighting their role alongside non-surgical methods for small, specific cases.
1 citations
,
April 1995 in “Annals of Plastic Surgery” This study describes the Mercedes incision technique, which may improve hair transplant results by reducing graft compression and row cropping, leading to a more natural appearance.
10 citations
,
June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that cultured mouse dermal papilla (mDP) cells can induce hair follicle neogenesis in de novo regenerated skin tissues grafted onto mice.
3 citations
,
July 2025 in “BMC Oral Health” In this study, researchers explored the use of natural materials in scaffold construction for dental bone preservation, suggesting it could offer better biocompatibility and bone regeneration compared to traditional grafting methods.
14 citations
,
May 2004 in “Annals of Plastic Surgery” This study found that muscle-only free flaps for skull coverage were associated with serious complications, suggesting that composite or thicker muscle flaps may reduce these risks.