53 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.
1 citations
,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” In this study, topical acyclovir significantly delayed hair growth initiation and completion in mice and reduced hair follicle size, suggesting potential inhibitory effects on hair growth.
January 2024 in “Advances in Dermatology and Allergology” This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options.
January 2014 in “Journal of Pigmentary Disorders” This review discusses age-related and environmental factors affecting scalp hair changes in women, highlighting diagnostic complexities and ongoing research into targeted treatments, without reporting new clinical results.
49 citations
,
August 2022 in “Materials Today Bio” This review discusses 3D bioprinting methods for urological diseases, noting its potential to create functional organs for transplantation despite challenges in replicating organ complexity and material limitations.
38 citations
,
November 2000 in “Hastings Center Report” This paper argues that both the modern biomedical model and existing supplementary frameworks fail to adequately capture the complexities of empathy and healing within the context of postmodern thinking.
14 citations
,
January 2001 in “Primary Care Update for Ob/gyns” This review discusses the challenges in addressing female sexual dysfunction, focusing on the complexities of female sexual response, levels of dysfunction, clinical identification, and existing treatments, but presents no new clinical findings.
11 citations
,
November 2021 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This guideline reviews the diagnosis and treatment of malignant cutaneous angiosarcomas, highlighting the complexity of treatment and the importance of early detection despite non-specific clinical presentations.
8 citations
,
November 2025 in “Journal of Translational Medicine” This review highlights challenges in developing drugs targeting the Wnt/β-Catenin signaling pathway for cancer due to its complexity and essential roles in normal tissue. It explores targeted protein degradation technology as a promising strategy to overcome these challenges, suggesting potential new avenues for drug development.
8 citations
,
December 2022 in “Nature Reviews Endocrinology” This review discusses the roles of sex hormones in COVID-19 progression and highlights conflicting evidence on their protective effects and the complexity of sex and gender influences on the disease.
6 citations
,
January 2005 in “Biology of Blood and Marrow Transplantation” This article reviews various models of graft-versus-host disease, highlighting the complexity of its mechanisms and the challenges in interpreting histopathologic data; it reports no new results.
4 citations
,
February 2022 in “JEADV Clinical Practice” This review discusses the diverse range of skin manifestations in children with COVID-19 and highlights the complexity of clinical assessment due to varied presentations; it reports no new clinical findings.
3 citations
,
January 2011 in “Female pelvic medicine & reconstructive surgery” This review discusses the impact of hormones on female sexual function and dysfunction, highlighting the complexity and gaps in basic research, and reports no new clinical findings.
2 citations
,
March 2023 in “The Lancet. Respiratory medicine” This narrative discusses the personal experiences of individuals suffering from long COVID, highlighting the challenges and complexities of living with the condition, but reports no new clinical findings.
2 citations
,
October 2018 in “Journal of Mind and Medical Sciences” This article reviews surgical and medical management strategies for endometriosis-related abdominal-pelvic pain, emphasizing the complexity and ongoing challenges in achieving long-term pain control and disease management.
1 citations
,
December 2024 in “Qeios” This study found that a five-dimensional model of personality perception from men's facial photographs better captures the complexity of face perception than the traditional two-dimensional Valence-Dominance model, highlighting overlaps with personality structures known from differential psychology.
1 citations
,
April 2016 in “Journal of Reproductive Health and Medicine” This article reviews challenges in diagnosing new-onset SLE during pregnancy, emphasizing the complexity of distinguishing it from normal pregnancy changes and preeclampsia, and reports no new results.
1 citations
,
December 2011 in “Journal of The American Academy of Dermatology” This book review examines various classification and treatment methods for acne scars, emphasizing the complexity and need for multiple therapeutic approaches, but reports no new clinical results.
January 2026 in “Immune Network” This review discusses the heterogeneity of Tregs in normal and tumor environments, emphasizing the complexity of targeting tumor-resident Tregs while maintaining systemic immune tolerance, but reports no new findings.
January 2025 in “Dermatology Review” This paper outlines the clinical features of artefactual skin disorder, emphasizing the complexities in diagnosing the self-inflicted lesions that patients deny, and underscores the importance of integrating dermatological, psychiatric, and psychological treatment approaches.
January 2025 in “Pakistan Veterinary Journal” This report describes a pancreatic mixed acinar-neuroendocrine carcinoma in a cat, underscoring its diagnostic complexity and the need to consider it in diagnoses of pancreatic masses with mixed features.
July 2022 in “Fayoum University Medical Journal” This paper discusses polycystic ovarian syndrome (PCOS) and reports no new results; the authors highlight the complexity and heterogeneity of this endocrine disorder.
September 2016 in “Princeton University Press eBooks” The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
January 2011 in “Dermatologic Clinics” This review examines challenges in managing hair loss in women, emphasizing the complexity of diagnosis, treatment options like antiandrogens and minoxidil, and the need for long-term management, but reports no new clinical results.
June 2026 in “International Journal of Homoeopathic Sciences” This case report from Dr Batra's® Homeopathy Clinic describes a 51-year-old male with chronic facial melasma, where individualized homeopathic treatment and integrative skin therapies led to sustained improvement in pigmentation, complexion, and skin texture over time.
1308 citations
,
March 1998 in “Journal of bone and mineral research” This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
67 citations
,
May 2007 in “Journal of Cosmetic Dermatology” This study found that topical formulations including extracts from Cuscuta reflexa, Citrullus colocynthis, and Eclipta alba significantly accelerated hair growth initiation and completion in rats, indicating potential benefits for treating alopecia.
41 citations
,
August 2007 in “European Journal of Gastroenterology & Hepatology” This case report documents a reversible instance of complete body hair loss (alopecia universalis) in a patient undergoing chronic hepatitis C treatment with pegylated interferon alpha-2b and ribavirin, with hair regrowth observed within three months after therapy completion.
27 citations
,
April 2005 in “Journal of Chemotherapy” This study reported two cases of alopecia universalis triggered by PEG-interferon and ribavirin therapy for chronic hepatitis C, with hair regrowth observed after therapy completion or withdrawal.
26 citations
,
July 2019 in “Fertility and Sterility” This study found that reproductive gynecologists are the primary source of referrals for male infertility evaluations, with many men referred before completing a male factor investigation even when using assisted reproductive technologies or lifestyle factors like testosterone replacement.