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The study reports that the AVET system showed higher efficiency in transfecting cultured human keratinocytes compared to SuperFect and PrimeFector, with AVET reaching levels of enzyme activity similar to normal cells in keratinocytes from lamellar ichthyosis patients.

This article reviews the process of obtaining NHS ethical approval for research involving children and highlights the challenges faced in interdisciplinary work, without presenting new research results.

In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.

In this review of autonomous robotic surgery, the authors explore the integration of AI and machine learning in surgical procedures, detailing both the advancements and challenges of these technologies, including ethical concerns and current regulatory frameworks.

This study found that tyramine-linked hyaluronan gel effectively supports the 3-D culture of ovarian follicles, facilitating the maturation of functional metaphase II oocytes that can develop into blastocysts.

Timely diagnosis of SLE is crucial due to symptom overlap with fibromyalgia.

This review outlines recent progress in CRISPR/Cas9 genome editing, discussing its structure, mechanisms, and the use of genetic, chemical, and physical strategies to enhance precision and reduce off-target effects despite some persistent challenges for clinical application.

This review discusses alginate-based delivery systems for probiotics, highlighting recent advances, challenges, and future directions, but reports no new clinical findings.

This study found that cyclosporine-A might significantly increase the risk of cerebral venous and arterial thrombosis in patients with aplastic anemia.

This review discusses the roles of prostaglandins in the nervous system and their therapeutic potential for neurological diseases, noting their complex interactions with immune cells and signaling pathways.

This review reports that chitosan-based systems with metal nanoparticles and polyphenols may enhance wound healing by improving the bioavailability and stability of these compounds, suggesting a potential new approach for chronic and diabetic wounds.

This study found that patient-reported outcomes were similar between neoadjuvant endocrine therapy and chemotherapy in premenopausal breast cancer patients, but future perspective was significantly better with endocrine therapy.

This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.

This literature review reports that lavender essential oil exhibits various medicinal benefits, such as antibacterial and antioxidant properties, and that incorporating nanotechnology could enhance its effectiveness by improving solubility and stability.

Early recognition and treatment of SLE can improve outcomes in patients with complex symptoms.

This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.

This review discusses recent advancements in the development and use of polymer-based nanohydrogels for topical drug delivery, noting their potential to enhance drug loading, release control, and skin penetration for treating dermatological conditions.

This review discusses the therapeutic effects of stem cell therapy in various diseases and emphasizes the need for controlled differentiation and further large-scale trials, but reports no new findings.

This study demonstrated that hyaluronan gel is a promising biomaterial for 3-D in vitro culture of mouse ovarian follicles, supporting the production of fertilizable metaphase II oocytes.

This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.

This study proposes creating formal educational programs for dermatologists to improve care for African American patients by addressing the lack of training in hair care practices and complications associated with cultural styles like braids and wigs, thereby aiming to enhance health outcomes and healthcare equity.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

This review discusses the absence of clinical trials on natural ingredients for managing Central Centrifugal Cicatricial Alopecia and highlights a need for more research.

In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.

This review posits that alopecia in PCOS results from the interaction between local follicular signaling failures, insulin resistance, inflammation, and genetic predispositions, rather than solely from androgen excess, and recommends a systems-level framework for its management.

This study found that suspension culture was more effective than hydrogel-based systems for maintaining spheroid morphology and differentiation of human iPSC-derived definitive endoderm cells.

This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.

This study found that women with genetic hair loss experienced significant improvements in hair density, count, and thickness when treated with both Rehmannia root extract and microneedling therapy, with the combination showing the greatest benefits compared to each treatment alone.

This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.

This review discusses the clinical significance, mechanisms, and treatment options of insulin resistance, emphasizing its impact on endocrine diseases and the need for further research into inflammatory cytokines.