16 citations,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
39 citations,
September 2017 in “The Open Rheumatology Journal” Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.
3 citations,
September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
57 citations,
May 2014 in “Molecular Phylogenetics and Evolution” The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
9 citations,
December 2021 in “Androgens” Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
114 citations,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
7 citations,
December 2010 in “Current Drug Therapy” Anti-complement agents could effectively treat autoimmune diseases with fewer side effects.
13 citations,
October 2010 in “Pharmacogenomics” Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
Finding functions for unknown GPCRs is hard but key for making new drugs.
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
11 citations,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
2 citations,
October 2022 in “Current Allergy and Asthma Reports” Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
134 citations,
January 2019 in “American journal of clinical dermatology” Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
1 citations,
January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
149 citations,
July 2002 in “Dermatologic clinics” Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
359 citations,
September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
305 citations,
July 2016 in “International Journal of Biological Macromolecules” Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
266 citations,
November 2013 in “European Journal of Epidemiology” The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
80 citations,
August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
78 citations,
October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
53 citations,
June 2012 in “Annales d'Endocrinologie” The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
43 citations,
June 2018 in “Clinics in dermatology” People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
19 citations,
November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
18 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
14 citations,
April 2014 in “International Journal of Cosmetic Science” Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.
9 citations,
January 2017 in “Journal of Clinical and Diagnostic Research” Most pregnant women experience skin changes, mainly increased pigmentation, and some develop pregnancy-related skin conditions and infections.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
3 citations,
January 2017 in “International journal of research - granthaalayah” The traditional hair pack effectively reduced dandruff without any side effects.