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    Did you mean Complement Component 3?
    Glossary Complement Component 3

    crucial immune protein aiding pathogen destruction and inflammation

    Complement Component 3 (C3) is a crucial protein in the immune system's complement pathway, which helps the body fight infections and clear damaged cells. It plays a central role in activating the complement system, leading to the destruction of pathogens and the promotion of inflammation. Deficiencies or malfunctions in C3 can lead to increased susceptibility to infections and autoimmune diseases.

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    1. SnapshotDx Quiz: May 2020 2020
    2. Lichen simplex chronicus positive for C5b-9/MAC, IgD and C3c as a result of recurrent bacterial hair follicular unit infection Our Dermatology Online · 2020
    3. Combined C3b and Factor B Autoantibodies and MPGN Type II New England Journal of Medicine · 2011 · 97 citations
    4. Central centrifugal cicatricial alopecia amalgamated with alopecia areata: immunologic findings Our Dermatology Online · 2014 · 1 citations
    5. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2023
    6. EMQN best practice guidelines for molecular genetic testing and reporting of 21-hydroxylase deficiency European Journal of Human Genetics · 2020 · 94 citations
    7. Potential Therapeutic Applications of Bee Venom on Skin Disease and Its Mechanisms: A Literature Review Toxins · 2019 · 39 citations
    8. Natural Sources of Therapeutic Agents Used in Skin Conditions Life · 2024 · 35 citations
    9. Antigen presenting cells in the skin of a patient with hair loss and systemic lupus erythematosus. PubMed · 2009 · 9 citations
    10. Hydrogels: current biomedical applications and future directions Molecular Biomedicine · 2026
    11. Polymeric Nanohydrogel in Topical Drug Delivery System International journal of nanomedicine · 2024
    12. Genetic association of complement component 2 polymorphism with systemic lupus erythematosus Tissue Antigens · 2015 · 12 citations
    13. Serum levels of ifn-γ, complement component c3 c4 and vitamin d3 in the prognosis of patients with alopecia areata prospective teachers 3C Empresa Investigación y pensamiento crítico · 2023 · 2 citations
    14. Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling Frontiers in Bioengineering and Biotechnology · 2026
    15. Transgender Competent Provider Kansas journal of medicine · 2019 · 16 citations
    16. LB1774 Establishing competent morphogenetic fields for tissue pattern regeneration in skin organoids Journal of Investigative Dermatology · 2023
    17. A nanocomposite competent to overcome solubility and permeation issues of capsaicin and thiocolchicoside simultaneously in gout management: Fabrication of nanocubosomes Saudi Pharmaceutical Journal · 2024 · 6 citations
    18. A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies Wound Repair and Regeneration · 2014 · 35 citations
    19. Generation of germline-competent induced pluripotent stem cells Yearbook of Dermatology and Dermatologic Surgery · 2008
    20. New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes Reproductive Biology and Endocrinology · 2022 · 13 citations
    21. Bridging gaps and cultivating care: a call for culturally competent dermatological education for ethnic hair International Journal of Women’s Dermatology · 2025
    22. New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes Research Square (Research Square) · 2022
    23. Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils 2020 · 16 citations
    24. Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature Lupus Science & Medicine · 2019 · 17 citations
    25. Erythema Nodosum Leprosum Archives of Dermatology · 1977 · 5 citations
    26. Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus International Journal of Dermatology · 2000 · 64 citations
    27. Immunoregulatory mechanisms and stress hormones in psoriasis (part 1) International Journal of Dermatology · 1998 · 16 citations
    28. Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle Biological Reviews · 2014 · 120 citations
    29. Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures npj regenerative medicine · 2023
    30. Religious headwear and alopecia: considerations for dermatologists International Journal of Women’s Dermatology · 2023 · 4 citations