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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Hair follicle regeneration needs special conditions and young cells.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.