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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

CDP is crucial for lung and hair follicle cell development.

Stem cell niches support, regulate, and coordinate stem cell functions.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Both mouse and rat models are effective for testing alopecia areata treatments.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

GLI2 increases follistatin production in human skin cells.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.