89 citations,
November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
75 citations,
November 2007 in “Clinical endocrinology” Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
68 citations,
September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
66 citations,
February 2010 in “CrystEngComm” Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
55 citations,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
52 citations,
November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
50 citations,
May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
49 citations,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
48 citations,
October 2011 in “Sports Medicine” Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.
47 citations,
March 2004 in “European journal of endocrinology” Spironolactone plus finasteride reduces hirsutism more effectively.
45 citations,
January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
39 citations,
January 2012 in “Indian Dermatology Online Journal” Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
35 citations,
January 1993 in “International Journal of Dermatology” People with HIV and low T cell counts have more hair and scalp problems.
33 citations,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
32 citations,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
27 citations,
August 1999 in “Urology” Finasteride improves urinary function in men for 2 years.
26 citations,
June 2005 in “Journal of Molecular Endocrinology” Dutasteride is more efficient than finasteride, but individual results vary.
25 citations,
April 2006 in “British Journal of Dermatology” Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.
24 citations,
July 2018 in “Drug Design Development and Therapy” NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
24 citations,
September 2008 in “International Braz J Urol” Lovastatin doesn't improve lower urinary tract symptoms treatment.
23 citations,
June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
23 citations,
July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
20 citations,
December 2016 in “American Journal of Clinical Dermatology” Men prefer less invasive cosmetic procedures and need different treatment approaches than women.
20 citations,
August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
18 citations,
January 2011 in “Bioorganic & Medicinal Chemistry Letters” New hybrid compound found to effectively prevent hair loss.
18 citations,
June 2002 in “BJUI” Finasteride doesn't change rat testicle weight or sperm production.
18 citations,
April 2001 in “Bioorganic & Medicinal Chemistry Letters” The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
16 citations,
October 2019 in “Biological & Pharmaceutical Bulletin” Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.