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Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Finasteride may improve prostate cancer treatment outcomes.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Dosing time affects finasteride's effectiveness and safety in rats.

TLR2 is important for hair growth and can be targeted to treat hair loss.

Innovative methods are reducing animal testing and improving biomedical research.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.