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Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

TGF-β2 plays a key role in human hair growth and development.

Autophagy is important for human hair growth and health.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Nasolabial skin-fat grafts are good for nasal reconstruction with minimal scarring and no need for bolsters, but smoking may affect graft survival.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Olive leaf compound oleuropein helps grow hair in mice.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

The hydrogel speeds up skin wound healing and helps regenerate tissue.

Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.

Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.