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Combining Traditional Chinese Medicine and Western medicine can improve symptoms, hormone levels, and pregnancy outcomes in Polycystic Ovary Syndrome patients, but more research is needed.

Neurohormones help control skin health and could treat skin disorders.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.

The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Dsg1 is essential for maintaining a healthy skin barrier in mice.

Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.

PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

Blocking JAK-STAT5 signaling in mice leads to hair growth.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

The document concludes that proper recognition and treatment of skin appendage disorders are important for management.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.