16 citations
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October 2024 in “Journal of Paediatrics and Child Health” This systematic review highlighted significant psychosocial impacts of alopecia areata in children and adolescents, noting challenges such as reduced self-esteem, emotional distress, and social difficulties. The review underscored the need for further research to understand these effects comprehensively and guide clinical support.
7 citations
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March 2022 in “Journal of the American Academy of Dermatology” This article discusses the association of stressful life events with alopecia areata and their effects on patients' psychosocial outcomes, but it reports no new empirical findings.
5 citations
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October 2021 in “Scientific Reports” This study suggests that certain climate factors, particularly UV index and precipitation, may influence seasonal flare patterns in children with alopecia areata, especially those with atopic conditions.
3 citations
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April 2022 in “Biomolecules” This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.
July 2026 in “Quality in Sport” This review found that alopecia areata is driven by an inflammatory response and highlights the need for early, individualized treatment to address both hair loss and psychiatric comorbidities, although more research is needed for long-term management strategies.
In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case study, treatment with the selective JAK1 inhibitor upadacitinib significantly improved symptoms in a patient with refractory alopecia areata, vitiligo, ankylosing spondylitis, and allergic asthma-nasal syndrome, though a transient liver function abnormality was noted.
January 2026 in “Frontiers in Medicine” This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.
September 2025 in “International Journal of Medical Informatics” A machine learning model can predict scarring in lichen planopilaris using factors like vitamin D levels and diagnostic delay.
August 2025 in “Annals of Indian Psychiatry” In a cross-sectional study, 46% of patients with androgenetic alopecia were found to have depression of borderline to moderate severity, while 62% reported no impact on their quality of life, emphasizing the need for awareness of psychiatric comorbidities among dermatologists.
April 2025 in “Journal of the American Academy of Dermatology” The study has limitations, and future research should use better methods to improve treatment for children with hair loss.
January 2025 in “Dermatology Review” This paper outlines the clinical features of artefactual skin disorder, emphasizing the complexities in diagnosing the self-inflicted lesions that patients deny, and underscores the importance of integrating dermatological, psychiatric, and psychological treatment approaches.
November 2024 in “Thrombosis Journal” This review highlights potential links between inflammatory skin diseases like psoriasis and atopic dermatitis and hypercoagulable states, but notes that more research is needed to understand these connections and their clinical implications.
In this case report, off-label onabotulinumtoxin-A was successfully used to treat trichodynia, a painful scalp sensation associated with hair loss, in a patient unresponsive to conventional therapies.
February 2024 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study reviewed 562 alopecia areata patients in Colombia, observing a higher prevalence in women and common use of steroid injections and topical minoxidil as treatments.
Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.
This review examines the psychological effects of chronic hair diseases and reports no new findings, highlighting the impact on self-confidence, coping skills, and associated psychiatric conditions.
July 2019 in “International journal of contemporary medical research” This study found that dyslipidemia was more common in male patients with androgenetic alopecia than in controls, particularly among those with severe AGA, suggesting a higher risk of altered serum lipids.
11 citations
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November 2021 in “BMJ Open” This study reviews the epidemiology of alopecia areata in the UK, focusing on its links to mental health comorbidities, autoimmune/atopic associations, and common infection incidences.
January 2023 in “Journal of The American Academy of Dermatology” This study examined medical comorbidities and medications among women with vulvar lichen sclerosus, contributing insights for comprehensive treatment strategies, but does not report new clinical results.
September 2022 in “Frontiers in Immunology” This study reports that comorbidities and anti-androgen therapy were associated with lower SARS-CoV-2 vaccination rates among patients with androgenetic alopecia, emphasizing the need to promote vaccination within this group.
3 citations
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May 2021 in “Dermatologic Clinics” This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.
3 citations
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April 2019 in “Journal of psychosexual health” This review discusses the psychiatric and sexual comorbidities of PCOS, emphasizing the need for a multidisciplinary approach to manage sexual dysfunction due to high prevalence rates found in recent studies.
March 2022 in “IntechOpen eBooks” This review discusses the complexities and co-morbidities associated with polycystic ovary syndrome, including its impact on metabolic and psychological health, and reports no new clinical results.
62 citations
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April 2013 in “Steroids” This review discusses the age-related diagnostic challenges and comorbidities of polycystic ovarian syndrome and provides no new clinical findings; the authors emphasize the role of obesity in insulin resistance among affected women.
April 2020 in “Journal of the Endocrine Society” This study concluded that patients with type 3 acromegaly had higher comorbidities, greater disease activity, and increased mortality risk compared to those with type 1 and type 2 acromegaly, even after treatment adjustments.
April 2012 in “Journal of the American Academy of Dermatology” This study found that psoriasis patients had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to those without psoriasis.
This study found that patients with psoriasis had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to individuals without psoriasis.
April 2012 in “Journal of the American Academy of Dermatology” This study found that psoriasis patients had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to those without psoriasis.
15 citations
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August 2021 in “Reviews in endocrine and metabolic disorders” This review discusses hypopituitarism's bidirectional relationship with COVID-19 due to metabolic comorbidities and pituitary risks, but it reports no new clinical results.