May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Testosterone significantly affects urination differences between male and female mice.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” A gene variant causes patched hair loss in mice, similar to alopecia areata in humans.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
81 citations,
June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
64 citations,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The new method found new shared genetic areas linked to both Type 2 Diabetes and Prostate Cancer.
August 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The model successfully predicted new uses for existing drugs, like using certain hormonal and heart medications for respiratory and Parkinson's diseases, and a cancer drug for diabetes.
4 citations,
May 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Long-lasting COVID-19 symptoms like fatigue and breathing difficulties can persist for over 60 days, requiring ongoing care.
July 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Kashmiri women with PCOS have more Bifidobacterium in their gut.
August 2022 in “medRxiv (Cold Spring Harbor Laboratory)” The goal is to create a tool for patients to report their experiences with various hair and scalp disorders.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Neutrophil extracellular traps slow down hair follicle healing after injury.
29 citations,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
January 2012 in “Human health handbooks” Traditional Indian remedies are used for hair health, but more scientific evidence is needed to prove their safety and effectiveness.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
73 citations,
April 1999 in “Dermatologic Clinics” Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.
3 citations,
April 2017 in “Dermatologic Surgery” Laser hair removal can be an effective last-resort treatment for men with stubborn Alopecia Areata who want to be uniformly bald.
3 citations,
February 2002 in “Dermatologic Surgery” Using a handheld massage device during hair transplant significantly reduces pain for most patients.
August 2017 in “Companion animal” Focal alopecia in dogs has many causes and requires various tests for accurate diagnosis and treatment.
December 2004 in “Medicine” A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.
95 citations,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
8 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.
7 citations,
January 2019 in “Brazilian Journal of Pharmaceutical Sciences” Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.