Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This paper reviews the evolution of skin appendages and keratin-associated proteins among amniotes, proposing a model for their genetic divergence without new experimental results.

This study found that early-onset androgenetic alopecia in individuals of European ancestry is significantly associated with increased odds of Parkinson's disease and is influenced by specific genetic loci, including some linked to reduced fertility.

This study identified that 80% of a rural population in Ecuador uses medicinal plants like Aloe vera for treating hair conditions, highlighting the prevalence of ancestral plant knowledge.

In this study, analysis of over 800 Iranian patients with epidermolysis bullosa identified 15 with pathogenic PLEC variants, highlighting a correlation between variant locations and phenotypic manifestations of plectinopathies.

This study found six new genetic factors linked to early-onset androgenetic alopecia and its association with increased risk of Parkinson's disease and decreased fertility.

In this study, researchers found that two dominant haplotypes in the EDA2R/AR intergenic region have likely been shaped by demographic changes and selection during human evolution, particularly notable in African and non-African populations.

In this study, researchers found that the female plumage color variations in the common cuckoo are linked to the female-restricted genome and suggest this pattern is maintained by balancing selection, sharing ancestry with the oriental cuckoo.

This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.

This study identified multiple mutations in the 5 alpha-reductase-2 gene among male pseudohermaphrodites in the Dominican Republic, suggesting they do not share a common ancestry.

CCCA in women of African ancestry may be caused by PADI3 gene mutations and intense hair grooming.

Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.

In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.

This article reports that mutations in the PADI3 gene, affecting its activity or localization, cause uncombable hair syndrome and are linked to central centrifugal cicatricial alopecia, particularly among women of African ancestry.

This chapter discusses genetic polymorphisms related to phenotypes that differentiate between populations and reports no new results; it highlights the role of DNA technology in understanding human adaptation history.

This study found that mutations in the PADI3 gene, which is important for hair shaft formation, may contribute to central centrifugal cicatricial alopecia among patients.

This article discusses features, genetics, and diagnostic challenges of central centrifugal cicatricial alopecia in African American women but reports no new clinical results.

In this case-control study, researchers did not find genome-wide significant genetic variants for trichotillomania, but cases had higher polygenic risk for psychiatric disorders and certain neuropsychiatric-associated copy number variants.

Keratin gene clusters in humans and marsupials are similarly organized.

This study found that in men with high genetic risk factors for polycystic ovary syndrome, there was an associated increase in obesity, type 2 diabetes, coronary artery disease, and androgenic conditions, suggesting these genetic factors can act independently of ovarian function.

This review discusses trichotillomania and traction alopecia, focusing on their clinical features, diagnostic criteria, and treatment options, but it reports no new research findings.

In this study, the researchers found that mammalian hair likely evolved through the adaptation of existing structural proteins, as similar cysteine-rich α-keratins were identified in chicken and lizard genomes, suggesting pre-mammalian origins.

This review discusses the evolutionary history of keratins and reports no new results, highlighting key events that contributed to the development of mammalian hair and integument.

In a comparative genomic study, researchers observed significant genetic differences among the three chemical races of the alga Botryococcus braunii, leading them to propose reclassifying these races as distinct species based on their unique genomic characteristics.

This review discusses the epidemiology and cutaneous manifestations of lupus erythematosus, highlighting comparable incidence rates between cutaneous and systemic forms, but reports no new findings.

The researchers reported that cancer incidences are rising over time in developed countries, with potential carcinogenic drivers including advancing age, estrogen, decreasing vitamin D3, and Human Papillomavirus.

This article discusses the causes, development, treatment, and prevention strategies for pseudofolliculitis barbae and folliculitis keloidalis nuchae, but reports no new clinical results.

This article reviews the theory that certain cultural practices, like specific haircuts, contribute to common baldness but reports no new clinical findings.

This study found that faster algorithms for inferring ancestry in genomic data can better capture historical and functional insights into genome variation than traditional methods in large datasets like the UK Biobank.

This article reviews several benign skin conditions in newborns, emphasizing the importance of correct identification to prevent unnecessary concern and interventions, but reports no new clinical results.

This study found that certain tandem repeats predict darker hair color across diverse ancestry groups and can contribute to a polygenic score for hair color, independent of SNP variation.