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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Targeting colon cancer stem cells might lead to better treatment results.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Special fiber materials boost the healing properties of certain stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Fat cells in the skin help start healing and form important repair cells after injury.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Skin-derived precursors in hair follicles come from different origins but function similarly.