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Comprehensive screening for infections is crucial before starting JAK inhibitors in alopecia areata patients.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Minoxidil and photobiomodulation together improve hair growth better than minoxidil alone.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Both drugs lower DHT levels, with GI198745 being more effective.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

New compounds may soon be tested to treat excessive hair growth in women.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.

Compound 15a was effective in inhibiting 5α-reductase.

Microneedling combined with skinbooster effectively treats striae rubrae, with confocal microscopy confirming collagen changes.

Exercise and finasteride together improve ovary health in PCOS rats.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

TNF-alpha inhibitors can cause various immune-related skin issues.