26 citations
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May 2017 in “Lasers in Medical Science” This study found that combining ablative fractional CO₂ laser therapy with hair growth factors significantly increased hair density in men with androgenetic alopecia compared to using growth factors alone.
26 citations
,
January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
25 citations
,
June 2018 in “Clinical and Experimental Dermatology” This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.
24 citations
,
July 2019 in “Journal of Obstetrics and Gynaecology” This study found that a 12-week supplementation with a combination of insulin sensitizing agents, antioxidants, and vitamins significantly improved menstrual cyclicity, acne, and hirsutism in women with PCOS, with additional weight loss benefits in obese subjects.
23 citations
,
July 2018 in “BMC Complementary and Alternative Medicine” This study used association rule mining and network analysis to identify frequently combined herb sets for treating alopecia from 56 articles, highlighting the potential of Polygonum multiflorum, Angelica sinensis, and Ligusticum chuanxiong in traditional medicine and suggesting further bioinformatics research to understand their efficacy.
21 citations
,
January 1998 in “Urologia internationalis” This study found that combining dibenyline and finasteride for symptomatic BPH treatment offered modest improvements with fewer additional side effects compared to each drug alone.
20 citations
,
July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
19 citations
,
January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.
19 citations
,
August 2019 in “Expert Opinion on Therapeutic Targets” This review discusses emerging targets for developing drugs to treat hair loss and reports no new clinical results; the authors emphasize the potential for therapies that regenerate hair follicles.
19 citations
,
January 2019 in “Ginekologia Polska” This study found that combined Myo-inositol and D-chiro-inositol therapy improved metabolic and hormonal parameters, including weight, hormone levels, and skin conditions, in women with PCOS after 6 months.
19 citations
,
April 2014 in “Expert opinion on emerging drugs” This review discusses Hedgehog inhibitors for basal cell carcinoma treatment, noting tumor regression during therapy but also challenges like muscle toxicity and potential resistance; it reports no new clinical findings.
18 citations
,
December 2017 in “Medicine” This study found that combining celecoxib with chemotherapy improved overall survival, disease-free survival, and quality of life in gastric cancer patients with positive COX-2 expression without increasing adverse events.
18 citations
,
July 2015 in “Journal of cosmetic dermatology” This study observed that combining hair dyeing with sodium hydroxide relaxers drastically increased protein loss in Caucasian virgin dark brown hair, while ammonium thioglycolate or guanidine hydroxide relaxers caused less damage.
16 citations
,
November 2022 in “American Journal of Clinical Dermatology” 16 citations
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July 2020 in “Advances in Traditional Medicine” This study found that the combined ethanolic extract ethosome formulation of Phyllanthus niruri, Zingiber officianale, and Croton tiglium Linné showed better safety and less cytotoxicity for hair growth promotion compared to the petroleum ether formulations.
15 citations
,
June 2021 in “Medicina” This study found that combined intense pulsed light and low-level light therapy significantly improved ocular surface outcomes and quality of life for patients with meibomian gland dysfunction and dry eye disease.
15 citations
,
July 2016 in “Urologic Clinics of North America” This study found that combining 5-alpha reductase inhibitors with alpha-blockers provided the best symptomatic relief and reduced the risk of clinical progression for BPH, while PDE5 inhibitors could offset sexual side effects.
15 citations
,
November 2015 in “Journal of Dermatology and Dermatologic Surgery” This case study reports that combining platelet-rich plasma with intradermal triamcinolone acetonide improved hair regrowth and fiber diameter in one patient with alopecia areata compared to triamcinolone alone.
15 citations
,
October 2003 in “Dermatologic Surgery” This study found that combining drug therapy with hair grafts can regress male androgenetic alopecia from Hamilton type V to type III.
14 citations
,
May 2016 in “Therapeutic advances in urology” This review examines the use of tadalafil and finasteride as a combined therapy for BPH, suggesting it may effectively reduce treatment-related sexual adverse events and improve symptom relief.
14 citations
,
June 2014 in “World Journal of Urology” This study found that the herbal combination PRO 160/120 significantly improved nocturnal voiding frequency in patients with moderate-to-severe LUTS/BPH compared to placebo, with similar effectiveness to tamsulosin and finasteride.
13 citations
,
September 2020 in “International Journal of Molecular Sciences” This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
11 citations
,
January 2024 in “Gynecological Endocrinology” This narrative review on inositol use in PCOS treatment found positive results for myo-inositol alone and effective outcomes for a myo-inositol/D-chiro inositol combination at a 40:1 ratio, suggesting further research on other combinations like 66:1 to 100:1.
11 citations
,
March 2023 in “Stem Cell Research & Therapy” In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.
11 citations
,
June 2020 in “Dermatologic Therapy” This study suggests that combination therapies including minoxidil with either finasteride, low-level laser light therapy, or microneedling are more effective than minoxidil alone for treating androgenetic alopecia.
11 citations
,
April 2020 in “Journal of Dermatological Treatment” This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
11 citations
,
May 2016 in “Journal of Cutaneous Medicine and Surgery” This study found that skin diagnoses in rheumatology patients were often unrelated to their underlying rheumatologic diseases, highlighting the importance of collaboration between dermatologists and rheumatologists.
11 citations
,
August 2006 in “Cell Biology International” This study found that endothelin-1 increases adhesion and chemotaxis of amelanotic melanocytes on fibronectin, laminin, and collagen IV, potentially through changes in the actin cytoskeleton.
10 citations
,
January 2023 in “Journal of Orthopaedic Surgery and Research” This study found that combining Panax notoginseng saponins with bone mesenchymal stem cells significantly enhanced diabetic cutaneous ulcer healing in rats by reducing inflammation and promoting new epidermis formation through specific molecular pathways.
10 citations
,
December 2020 in “Dermatologic Therapy” This study found that topical minoxidil 5% gel and spironolactone 1% gel were both effective treatments for androgenetic alopecia, with a combination of both providing the best clinical response and achieving 100% effectiveness among participants.