15 citations
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November 2019 in “Cutaneous and Ocular Toxicology” This study investigated a liposomal hydrogel system for delivering minoxidil and tretinoin to treat androgenic alopecia, finding that the system enhanced skin permeation of minoxidil while retaining tretinoin on the skin and was non-irritating in animal tests, suggesting its potential effectiveness.
15 citations
,
January 2019 in “Gynecological Endocrinology” This article discusses the need for a globally standardized protocol for epidemiologic studies of polycystic ovary syndrome to improve study comparability and public health policy.
15 citations
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November 2017 in “Drug Development and Industrial Pharmacy” This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
15 citations
,
December 2016 in “Advanced Pharmaceutical Bulletin” This study found that N-acetyl-glucosamine-loaded nanostructured lipid carriers showed promise for skin lightening in healthy volunteers by reducing melanin distribution.
15 citations
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October 2016 in “Steroids” This study developed and validated a label-free assay using LC-MS to screen for S5αR inhibitors, identifying Thai herbal extracts, Impatiens balsamina L. and Curcuma longa L., as promising sources.
14 citations
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October 2021 in “Dermatology and Therapy” This study found that photoexposure significantly increased the gene expression of altered elastin, MMP12, and LOX, as well as the protein expression of tropoelastin and fibrillin-1, in skin models.
14 citations
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October 2020 in “Journal of ethnopharmacology” This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.
14 citations
,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
14 citations
,
April 2019 in “Genes” This study identified a genetic locus associated with coat type in domestic dogs, showing certain variants linked to single-coated breeds and suggesting potential regulatory roles.
14 citations
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June 2014 in “Journal of Pharmaceutical Sciences” This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.
14 citations
,
September 1954 in “Textile Research Journal” This study found that hair absorbs significant amounts of NaBr from solution, with absorption increasing linearly with solution concentration and additional effects noted with acidic or basic solutions.
13 citations
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September 2024 in “Frontiers in Pharmacology” This review highlighted the pharmacological potential of Mor, noting its protective effects on the kidneys, liver, bones, nervous system, heart, digestive system, skin, and lungs, as well as its anti-obesity and anti-inflammatory properties, revealing areas for future research.
13 citations
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January 2020 in “Nanoscale” Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.
13 citations
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March 2019 in “Journal of ethnopharmacology” This study found that Cacumen Platycladi volatile oil promotes dermal papilla cell proliferation and enhances hair growth in mice, outperforming minoxidil and showing no obvious cytotoxic effects.
13 citations
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February 2018 in “Bio-medical Materials and Engineering” This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
13 citations
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December 2017 in “CNS Neuroscience & Therapeutics” In this study, finasteride was found to inhibit the dopaminergic system and reduce open-field behaviors in adolescent male rats by decreasing dopamine levels and related proteins.
13 citations
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January 2017 in “Chemical & Pharmaceutical Bulletin” This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.
13 citations
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February 2020 in “Clinical, Cosmetic and Investigational Dermatology” In this study, men with androgenetic alopecia had lower BMI and waist-to-hip ratios than controls, but no significant association with hypertension or other lifestyle factors was observed.
13 citations
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December 2017 in “BMC Complementary and Alternative Medicine” In this study, the herbal complex of Houttuynia cordata, Perilla frutescens var. acuta, and green tea promoted hair growth in C57BL/6 mice, enhancing regrowth and follicle development compared to controls.
12 citations
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July 2020 in “International Journal of Pharmaceutics” This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.
12 citations
,
September 2018 in “International Journal of Cosmetic Science” This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.
12 citations
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December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
12 citations
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October 2017 in “Journal of Cosmetic Dermatology” This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.
12 citations
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June 2013 in “The Prostate” This study found that dutasteride more effectively inhibited androgen receptor signaling and reduced cell growth compared to finasteride in prostate cancer cell models, with varying sensitivities across different cell lines.
12 citations
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September 2012 in “Alcohol and Alcoholism” This study found that a week of daily alcohol exposure during late adolescence led to a long-term increase in alcohol preference in adulthood, highlighting the sensitivity of this age group to alcohol's effects.
12 citations
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May 2003 in “Journal of dermatological science” This study found that the heat shock cognate protein Hsc70 was differentially expressed by dihydrotestosterone treatment in SV40-transformed dermal papilla cells, suggesting its involvement in androgen action on these cells.
12 citations
,
October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.
12 citations
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November 2020 in “Journal of Dermatological Science” In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
11 citations
,
April 2021 in “Advanced synthesis & catalysis” This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.
11 citations
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January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.