research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
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research Differential Effects of Wnt5a on the Proliferation, Differentiation, and Inflammatory Response of Keratinocytes
Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.
research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
research Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency
A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer
sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
research New Substrates for Stem Cell Control
New materials help control stem cell growth and specialization for medical applications.
research Decorin Promotes Proliferation and Migration of ORS Keratinocytes and Maintains Hair Anagen in Mice
Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
research Effects of Flavonoid Derivatives on Human Microvascular Endothelial Cells
Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.
research Narrowband UVB Treatment Induces Expression of WNT7B, WNT10B, and TCF7L2 in Psoriasis Skin
Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.
research New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology
The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
research Impaired Differentiation Potential of CD34-Positive Cells Derived from Mouse Hair Follicles After Long-Term Culture
Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
research Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/β-Catenin Pathway in Dermal Papilla Cells
Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Development and Evaluation of Crystalline Inclusion Complex of Finasteride Using Electrospraying as a Novel Approach
Created finasteride complex to increase water solubility and drug release.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys Cahirinus and Scarring Mus Musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
research A Slow-Cycling LGR5 Tumor Population Mediates Basal Cell Carcinoma Relapse After Therapy
A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
research Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice
Low selenium levels can extend lifespan but worsen health issues.
research Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes
Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Maternal PPARγ Protects Nursing Neonates by Suppressing the Production of Inflammatory Milk
A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
research Enhanced Viability and Neural Differentiation Potential in Poor Post-Thaw Human Adipose-Derived Stem Cells by Agarose Multi-Well Dishes and Spheroid Culture
Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
research Mucocutaneous Manifestations of Endocrine Disorders
Skin symptoms can indicate endocrine disorders and have various treatments.
research The Browning of White Adipose Tissue: Some Burning Issues
Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Association Between Smoking and Hair Loss: Another Opportunity for Health Education Against Smoking?
Smoking may contribute to hair loss in men.
research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma
WNT10A helps esophageal cancer cells spread and keep renewing themselves.
research The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro
A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
research Alopecia Areata Patients Show Deficiency of FOXP3+CD39+ T Regulatory Cells and Clonotypic Restriction of Treg TCRβ-Chain, Highlighting the Immunopathological Aspect of the Disease
Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.