Search

everythinglearnresearchcommunity

for

Search:↓

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

New treatments for male hypogonadism are effective and should be personalized.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Genetic variations affecting skin structure play a key role in severe acne.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.