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    Glossary Collagenase

    enzyme that degrades collagen in tissues

    Collagenase is an enzyme that breaks down collagen, a key structural protein in the skin, bones, and connective tissues. This enzyme is crucial in processes like wound healing and tissue remodeling, as it helps to remove damaged collagen and make way for new tissue formation.

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    1. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    2. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression. PubMed · 2015 · 26 citations
    3. A randomized pilot study to compare hair follicle cell suspensions prepared using trypsin alone versus trypsin in combination with collagenase type I for transplantation in vitiligo Clinical and experimental dermatology · 2019 · 5 citations
    4. Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts The Korea Journal of Herbology · 2014 · 2 citations
    5. Localization patterns of collagens during growth of human scalp hair Journal of Dermatological Science · 1998 · 1 citations
    6. Distribution of Type XII and XIV Collagens in Bovine Dermis and Hair Follicles Connective tissue · 2001
    7. Localization of Type I Human Skin Collagenase in Developing Embryonic and Fetal Skin Journal of Investigative Dermatology · 1994 · 22 citations
    8. Expression of Basement Membrane Proteins and Interstitial Collagens in Dermal Papillae of Human Hair Follicles Journal of Investigative Dermatology · 1991 · 85 citations
    9. 115 Distributions of type XII and XIV collagens in adult skin and the anagen hair follicle Journal of Dermatological Science · 1995
    10. Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation Stem Cell Research & Therapy · 2017 · 316 citations
    11. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    12. Ultrastructural Resemblance of Basal Cell Epithelioma to Primary Epithelial Germ Journal of Cutaneous Pathology · 1978 · 47 citations
    13. Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages Journal of Dermatological Science · 1994 · 28 citations
    14. Structures of three polycystic kidney disease-like domains from<i>Clostridium histolyticum</i>collagenases ColG and ColH Acta Crystallographica Section D: Structural Biology · 2015 · 18 citations
    15. Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts Molecular & cellular proteomics · 2019 · 9 citations
    16. Characterization of factors that determine lentiviral vector tropism in skin tissue using an <i>ex vivo</i> model The Journal of Gene Medicine · 2011 · 7 citations
    17. [Methods for optimized cultivation of hair cells from C3H mice]. PubMed · 1989 · 6 citations
    18. Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development Molecules · 2025 · 4 citations
    19. Rise of stem cell therapies in aesthetics Clinics in Dermatology · 2021 · 4 citations
    20. Isolation and Cultivation of Skin-Derived Precursors Methods in molecular biology · 2018 · 3 citations
    21. Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractility-driven strain that inhibits fibril degradation bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 2 citations
    22. Clinical Snippets 2003 · 1 citations
    23. Comprehensive chemical, morphological, thermal, and biological characterization of Agave tequilana extract and chitosan-based dissolving microneedle arrays PLoS ONE · 2026
    24. Protective Effects of Schinus terebinthifolius Leaf Supercritical Fluid Extract Against UVC-Induced Oxidative Stress: A Com-Prehensive Gene Expression Study International Journal of Molecular Sciences · 2026
    25. Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology International Journal of Molecular Sciences · 2025
    26. Anti-aging effect of <i>Grateloupia elata</i> extract in skin Journal of Applied Biological Chemistry · 2025
    27. Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report Clinical Cosmetic and Investigational Dermatology · 2024
    28. Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study Lasers in medical science · 2024
    29. Cosmetic Potency of Puerariae Radix in Dermal Fibroblasts Journal of Physiology & Pathology in Korean Medicine · 2019
    30. Uçucu Yağlar ve Aromaterapinin Dermokozmetik Alanındaki Uygulamaları 2025