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120-150 / 973 results![Recent advances in exosomal non‐coding RNA‐based therapeutic approaches for photoaging](/images/research/42b6905c-b2db-40cd-bd28-5bab5b188660/small/33600.jpg)
research Recent advances in exosomal non‐coding RNA‐based therapeutic approaches for photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
![The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2](/images/research/554d079e-ac88-47cf-9f25-1626d37a1c49/small/27751.jpg)
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
![Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation](/images/research/240b5bef-4a5a-4931-8d86-4b542cfe1fb7/small/30281.jpg)
research Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation
Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
research Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats
Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.
research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep
The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
![Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration](/images/research/cb1bb92c-8be5-4a0d-ac73-bfe850c5aab8/small/20083.jpg)
research Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
![Wound Healing and the Use of Medicinal Plants](/images/research/fef93363-ad26-465a-a93d-84511de49b51/small/17599.jpg)
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
![The Management of Postacne Scarring](/images/research/423c472b-0454-4e97-854e-935ed4160b4f/small/28544.jpg)
research The Management of Postacne Scarring
New treatments for acne scars are safer and more effective because we understand the causes better.
![Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls](/images/research/f85b2dbf-d3b1-4f7a-9572-f4c62edb6ee0/small/5485.jpg)
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner
![Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis](/images/research/8bd29abe-94cf-4dfa-b0a5-9cf9d12ebaed/small/29331.jpg)
research Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research ENZYMES
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
![Scarless wound healing: Transitioning from fetal research to regenerative healing](/images/research/ba54216e-4bf4-4c13-be4b-35016b7ea3e2/small/12739.jpg)
research Scarless wound healing: Transitioning from fetal research to regenerative healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
![Cryopreservation of engineered hair follicle germs for hair regenerative medicine](/images/research/8acd6a6f-17e2-4a87-9eac-23e869074e03/small/33007.jpg)
research Cryopreservation of engineered hair follicle germs for hair regenerative medicine
DMSO and microfinger devices show promise for preserving hair grafts for hair loss treatments.
research Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway
![Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth](/images/research/dce0c1cf-4289-4bb6-86ce-703d84abbcf8/small/19271.jpg)
research Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
![Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells](/images/research/4a723287-6a2c-4175-8b6e-f95d65efa118/small/30936.jpg)
research Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
![Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling](/images/research/9da7894b-8345-4f21-a3cc-41daf29157e8/small/19267.jpg)
research Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling
Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
research Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
![Gene therapy for alopecia in type II rickets model rats using vitamin D receptor-expressing adenovirus vector](/images/research/ed7a7d17-2067-4ed2-831e-437a11e70b7d/small/23467.jpg)
research Gene therapy for alopecia in type II rickets model rats using vitamin D receptor-expressing adenovirus vector
Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.
![Isolation of epithelial stem cells from dermis by a three-dimensional culture system](/images/research/ea81d6c2-f577-4e20-a166-41cbde522568/small/26610.jpg)
research Isolation of epithelial stem cells from dermis by a three-dimensional culture system
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
![The Immune Functions of Keratinocytes in Skin Wound Healing](/images/research/5c6b45b2-a4ba-4e28-abc4-8e4371220682/small/19263.jpg)
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
![Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection](/images/research/bf659cbc-cfd6-4b62-8ad5-e622772a7af0/small/35182.jpg)
research Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection
Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.
![Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth](/images/research/4b052e06-5109-4c93-a6bb-a15ddc18b2fb/small/14383.jpg)
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
![Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study](/images/research/d17e7fdb-fae3-4e04-9267-0acb8ed61fca/small/27859.jpg)
research Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study
Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.