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    Glossary Collagen

    protein providing structure and strength to connective tissues

    Collagen is a protein that serves as a key structural component in various connective tissues, including skin, hair, nails, bones, and tendons. It provides strength and elasticity, helping to maintain the integrity and resilience of these tissues. As we age, collagen production decreases, which can lead to signs of aging such as wrinkles and weakened joints.

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    1. A Novel Marker of Tissue Junctions, Collagen XXII Journal of Biological Chemistry · 2004 · 226 citations
    2. Role of macrophages in collagen resorption during hair growth cycle Journal of Ultrastructure Research · 1969 · 119 citations
    3. Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization American Journal of Pathology · 2003 · 109 citations
    4. Life before and beyond blistering: The role of collagen XVII in epidermal physiology Experimental Dermatology · 2018 · 63 citations
    5. The 800-nm diode laser irradiation induces skin collagen synthesis by stimulating TGF-β/Smad signaling pathway Lasers in Medical Science · 2011 · 59 citations
    6. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    7. Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy Stem Cell Research & Therapy · 2020 · 48 citations
    8. Collagen and Fractionated Platelet-Rich Plasma Scaffold for Dermal Regeneration 2016 · 42 citations
    9. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    10. Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis Matrix Biology · 2005 · 38 citations
    11. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    12. Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs Journal of Cosmetic Dermatology · 2015 · 36 citations
    13. Co‐culture of Human Hair Follicles and Dermal Papillae in a Collagen Matrix The Journal of Dermatology · 1990 · 36 citations
    14. Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study Clinical, cosmetic and investigational dermatology · 2020 · 34 citations
    15. Lack of Collagen VI Promotes Wound-Induced Hair Growth Journal of Investigative Dermatology · 2015 · 32 citations
    16. Measuring collagen injury depth for burn severity determination using polarization sensitive optical coherence tomography Scientific Reports · 2022 · 31 citations
    17. Collagen/Chitosan Gels Cross-Linked with Genipin for Wound Healing in Mice with Induced Diabetes Materials · 2021 · 31 citations
    18. Proliferation and differentiation of organoid hair follicle cells co-cultured with fat cells in collagen gel matrix culture British Journal of Dermatology · 1998 · 30 citations
    19. Epidermal Stem Cells Cultured on Collagen-Modified Chitin Membrane Induce In Situ Tissue Regeneration of Full-Thickness Skin Defects in Mice PLoS ONE · 2014 · 28 citations
    20. Collagen-type synthesis in human-hair papilla cells in culture Archives of Dermatological Research · 1988 · 28 citations
    21. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    22. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression. PubMed · 2015 · 26 citations
    23. Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain International Journal of Cancer · 2011 · 24 citations
    24. Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration Journal of Bionic Engineering · 2021 · 23 citations
    25. Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing Wound Repair and Regeneration · 2013 · 22 citations
    26. Novel Collagen Sponge Reinforced with Polyglycolic Acid Fiber Produces Robust, Normal Hair in Murine Hair Reconstitution Model Tissue Engineering · 2004 · 22 citations
    27. Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage International Journal of Dermatology · 2017 · 20 citations
    28. Collagen immobilization onto the surface of artificial hair for improving the tissue adhesion Journal of Adhesion Science and Technology · 2000 · 18 citations
    29. Natural Melanogenesis Inhibitor, Antioxidant, and Collagen Biosynthesis Stimulator of Phytochemicals in Rice Bran and Husk Extracts from Purple Glutinous Rice (Oryza sativa L. cv. Pieisu 1 CMU) for Cosmetic Application Plants · 2023 · 18 citations
    30. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations