11 citations
,
January 1976 in “International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine” This study found that a single X-radiation treatment in rat skin reduced collagen concentration over multiple hair-cycles by diminishing the fibroblasts' capacity for proline hydroxylation, potentially contributing to delayed skin lesions.
10 citations
,
January 2024 in “Dermatology Research and Practice” This randomized, double-blind, placebo-controlled study found that a supplement containing hydrolysed collagen and vitamin C (Absolute Collagen) improved skin, scalp, and hair over 12 weeks when taken daily or every other day.
10 citations
,
May 2020 in “Clinical and Experimental Health Sciences” This study found that Tideglusib at 50nM stimulated Type-I collagen production in human gingival fibroblasts and osteoblasts, suggesting potential benefits for bone regeneration.
10 citations
,
January 2009 This study suggests that collagen XVIII and its variant endostatin may play a role in regulating Wnt-signaling in hair follicles, affecting wound healing and skeletal development in mice.
9 citations
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August 2024 in “Tissue Engineering and Regenerative Medicine” In this study, researchers suggest that strategic early intervention during fetal wound healing could lead to significantly improved long-term skin regeneration outcomes.
9 citations
,
January 2022 in “Theranostics” This review discusses the role of collagen XVII in maintaining stem cell niches and its impact on skin aging and wound repair, without reporting new clinical results.
9 citations
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January 1990 in “Skin Pharmacology and Physiology” This study observed that 67 kDa keratin was expressed homogeneously only in epidermis derived from hair follicle explants, differing from other culture methods where expression was delayed and patchy.
8 citations
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November 2019 in “Tissue Engineering Part A” In this study, collagen scaffolds functionalized with heparin and growth factors significantly enhanced long-term skin regeneration and growth in a sheep model of fetal skin defect, suggesting potential for prenatal spina bifida treatment.
8 citations
,
April 2014 in “Anti-Cancer Drugs” In this study, PTH–CBD displayed dose-dependent effects in reducing hair loss and enhancing hair regrowth in a mouse model of chemotherapy-induced alopecia.
7 citations
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May 2023 in “Animals” This study observed that Fraser’s dolphins exhibit remarkable skin healing abilities, with type I collagen prevalent in normal skin and type III collagen emerging during early wound healing before returning to normal configuration, suggesting insights for human clinical wound management.
7 citations
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April 2020 in “Applied Sciences” In this study, ultrasound was found to alter the distribution of fibronectin in collagen hydrogels, leading to enhanced microtissue formation, suggesting potential applications in tissue engineering.
7 citations
,
January 2011 Collagen XVIII is crucial for maintaining tissue structure and function in the brain, kidneys, and hair.
6 citations
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April 2025 in “Food Bioscience” This study found that fish scale collagen peptide significantly promoted wound healing in mice, with the <1 kDa fractions enhancing collagen synthesis and reducing inflammation, suggesting potential clinical benefits.
6 citations
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May 2023 in “International journal of molecular sciences” This study supports using mesenchymal stem cells cultured with collagen to accelerate skin wound healing in mice and canines, by enhancing epidermal repair and promoting factors essential for skin recovery.
6 citations
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March 2023 in “Materials” In this study, researchers developed an acellular bioscaffold made from ovine tendon collagen with an antibacterial coating for treating skin wounds. They found that genipin crosslinking improves the scaffold's properties, and with plasma polymerisation, it enhances antibacterial activity, potentially benefiting wound healing.
6 citations
,
April 2001 in “The Anatomical Record” This study introduces a method for determining the orientation of collagen fibers in skin by analyzing the anisotropic shape of hair pores, which may aid in skin grafting procedures.
6 citations
,
January 1990 in “The Journal of Dermatology” This study successfully developed a method to culture human hair follicle cells without a biological feeder layer, maintaining cell differentiation for a month.
5 citations
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November 2023 in “Journal of Investigative Dermatology” This study observed that cutaneous microwounds created by fractional photothermolysis heal differently from typical wounds, displaying rapid re-epithelialization and limited inflammation, which may help reduce scar formation by delaying collagen remodeling and minimizing myofibroblast activation.
5 citations
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January 2012 in “Journal of nutrition & food sciences” This study found that a nutritional supplement containing peptides, lipids, hyaluronic acid, and collagen improved skin, hair, and nail dryness, with significant benefits noted for those with severe symptoms.
5 citations
,
January 2012 in “Journal of Tissue Science & Engineering” In this study, collagen I decellularized scaffolds enhanced the growth and melanotic properties of hair follicle melanocytes, suggesting their potential as effective carriers for transplantation in vitiligo treatment.
4 citations
,
March 2021 in “Journal of Histotechnology” In this study, researchers observed that hidradenitis suppurativa lesions were associated with reduced collagen and elastin, and increased neovascularization in areas with chronic inflammation.
4 citations
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July 2021 in “Journal of dermatology & dermatologic surgery” This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.
4 citations
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February 1983 in “Journal of periodontology” Among young rats, this study found that a liquid protein diet significantly affects body condition but has minimal impact on gingival collagen metabolism.
3 citations
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November 2020 in “Planta medica international open” This study reported that plant-produced basic fibroblast growth factor effectively promoted cell proliferation and collagen production in vitro, suggesting potential applications in cosmetics for antiaging and hair growth.
3 citations
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June 2017 in “Aesthetic plastic surgery” This study reported that novel adipose slurry injections improved rhytides and dermis density in patients receiving facial wrinkle treatments based on evaluations at multiple follow-up intervals.
3 citations
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January 2022 in “Burns & Trauma” This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
3 citations
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January 2020 in “PubMed” This study found that using insulin-like growth factor 1 with bone marrow-derived mesenchymal stem cells in a collagen-chitosan scaffold enhanced wound healing and hair follicle regeneration in rats.
3 citations
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January 2014 Collagen XVIII and Bmx tyrosine kinase are important for hair growth and skin cancer development.
3 citations
,
October 1994 in “Medical Molecular Morphology” This study observed that the lower part of vibrissa hair roots in adult Wistar rats receives a richer blood supply and structural protection, compared to the upper part.
3 citations
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July 1990 in “PubMed” This study demonstrated that plucked human hair follicles cultured in a collagen gel matrix developed spike-like structures, suggesting a useful method to study outer root sheath cell growth and differentiation in vitro.