research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
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research Androgenetic Alopecia: Treatments and Efficacy
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Sp6 Downregulation of Follistatin Gene Expression in Ameloblasts
Sp6 promotes tooth development by reducing follistatin levels.
research Review of the Effects of 17α-Estradiol in Humans: A Less Feminizing Estrogen with Neuroprotective Potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Adverse Health Effects of Androgen Use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Hair Growth Effect of Minoxidil
Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research The Endocrinology of Baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Nutrition of Women with Hair Loss During Menopause
Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
Alternative treatments show promise for hair growth beyond traditional methods.
research Activity of Type 1 5α-Reductase Is Greater in the Follicular Infrainfundibulum Compared with the Epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research Clinical Review 74: Dermatological Manifestations of Endocrine Disorders
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research Human Platelet Lysate Versus Minoxidil Stimulates Hair Growth by Activating Anagen Promoting Signaling Pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms Behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin with Marilex in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
research Alfatradiol (0.025%) - An Effective and Safe Treatment Option for Androgenetic Alopecia in Women and Men
Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Fibroblast Heterogeneity and Tertiary Lymphoid Tissues in the Kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats
Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Hirsuties
Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
research Potential Factors Contributing to Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.