research Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
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research The Wound Healing of Fractional Photothermolysis Mimics Scarless Healing with Minimal Myofibroblast Activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research A Mechanism for Topical Cutaneous Calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Ectoin Attenuates Cortisone-Induced Skin Issues by Suppression of GR Signaling and the UVB-Induced Overexpression of 11β-HSD1
Ectoin helps prevent cortisone-induced skin problems and supports skin health.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Polyphenol-Mediated Biomimetic Mineralization of Sacrificial Metal-Organic Framework Nanoparticles for Wound Healing
New wound healing method using nanoparticles in a gel speeds up healing and reduces infection and inflammation.
research Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing
Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Menopause and Its Effects on Skin and Hair
Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.
research Bioactive-Based Cosmeceuticals: An Update on Emerging Trends
Natural ingredients in cosmeceuticals are beneficial for skin and hair health with few side effects.
research Safety Concerns Regarding 5α Reductase Inhibitors for the Treatment of Androgenetic Alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Minoxidil Specifically Decreases the Expression of Lysine Hydroxylase in Cultured Human Skin Fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
research Hyperadrenocorticism (Cushing’s Disease or Syndrome) in Dogs: Treatment Approaches and Prognosis
Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
research Leucaena Leucocephala: A Nutritional Profile
Leucaena leucocephala is nutritious but needs careful processing to remove toxins.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Effect of Estrogens on Skin Aging and the Potential Role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Biosynthesis of Dihydrotestosterone by a Pathway That Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line
Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.