research Allosteric Interactions Prime Androgen Receptor Dimerization And Activation
Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
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research Blood Group O and Post-COVID-19 Syndrome
People with blood group O may have a higher risk of developing post-COVID-19 syndrome.
research Developing Patient-Reported Outcome Measure for Hair and Skin Disorders
The goal is to create a tool for patients to report their experiences with various hair and scalp disorders.
research A Systematic Review and Meta-Analysis of Polycystic Ovary Syndrome and Mental Health Among Black Asian Minority Ethnic Populations
Polycystic Ovary Syndrome (PCOS) increases the risk of mental health disorders, but its impact on Black Asian Minority Ethnic groups isn't fully known.
research Cell Surface Receptor Kinase FERONIA Linked to Nutrient Sensor TORC Signaling Controls Root Hair Growth at Low Temperature Linked to Low Nitrate in Arabidopsis Thaliana
A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.
research Induction of Hyperandrogenism and Insulin Resistance Differentially Modulates Ferroptosis in Uterine and Placental Tissues of Pregnant Rats
HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
research Protein Kinase C Is a Key Target for Attenuation of Leigh Syndrome by Rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
research A Direct Link Between Prss53, Hair Curvature, and Skeletal Dysplasia
The gene Prss53 affects hair shape and bone development in rabbits.
research Early Skin Seeding Regulatory T Cells Modulate PPARγ-Dependent Skin Pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research De Novo Assembly and Annotation of Asiatic Lion (Panthera Leo Persica) Genome
The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
research Finding Long-COVID: Temporal Topic Modeling of Electronic Health Records from the N3C and RECOVER Programs
Long-COVID has diverse, long-term health impacts, especially in young people.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
research Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024
Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.
research Armadillo Repeat Only Proteins Are Crucial for the Function of Plant CNGC Channels
Armadillo Repeat Only proteins are essential for proper plant growth and response by regulating calcium channels.
research The 5α-Reductase Inhibitor Finasteride Reduces Opioid Self-Administration
Finasteride may help reduce opioid use.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
The model successfully predicted new uses for existing drugs, like using certain hormonal and heart medications for respiratory and Parkinson's diseases, and a cancer drug for diabetes.
research Bifidobacterium Is Enriched in Gut Microbiome of Kashmiri Women with Polycystic Ovary Syndrome
Kashmiri women with PCOS have more Bifidobacterium in their gut.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
research MiR-29 Is an Important Driver of Aging-Related Phenotypes
miR-29 is a key factor that accelerates aging.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Conflicting Auxin-Phosphate Signals Impact on RSL2 Expression and ROS Homeostasis Linked to Root Hair Growth in Arabidopsis
Auxin helps root hairs grow in high phosphate by affecting ROS and involving RSL2 and RSL4.
research Remodelling of Cytoskeleton and Plasma Membrane Proteins Contributes to Drought Sensitivity of Arabidopsis Rhd2 Mutant
The Arabidopsis rhd2 mutant is more sensitive to drought because of changes in cell membrane proteins and cell structure.
research Guadalupe Fur Seal Alopecia: A Metabolic Syndrome Associated to Climatic Anomalies?
Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.
research GTL1 Is Required for a Robust Root Hair Growth Response to Avoid Nutrient Overloading
GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.
research In Vivo Imaging of Mammary Epithelial Cell Dynamics in Response to Lineage-Biased Wnt/β-Catenin Activation
Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
research AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Activates Dermal Papilla Cells to Promote Hair Growth
A peptide from hair follicle stem cells promotes hair growth by activating specific skin cells.
research More Than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis
COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.