June 2026 in “Domestic Animal Endocrinology” This study found that hair follicle gene expression varies between Angus and Brahman cattle and responds to growth-promoting treatments, which may reflect breed differences in adaptability to cold stress.
1 citations
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August 2024 in “Journal of Dermatological Science” Cold shock therapy may help hair grow by increasing certain proteins.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study investigated differences in gene expression in the mammary glands of SLICK and wild-type Holstein cattle, finding limited differences overall but identifying enriched pathways related to arachidonic acid metabolism and oxytocin production, which merit further exploration.
January 2024 in “Wiadomości Lekarskie” This preclinical study found that exercise-induced extracellular vesicles delayed breast cancer tumor growth in mice, potentially by enhancing the immune response within the tumor microenvironment.
April 2023 in “Journal of Investigative Dermatology” This study found that an automated tumor-infiltrating lymphocyte classification algorithm identified thin melanomas with less immune response, which were associated with higher mortality compared to other cases in the study.
2 citations
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September 2025 in “BMC Genomics” This study found that maize root hairs respond differently to cold stress based on severity, with mild cold allowing limited growth through adaptive remodeling, while severe cold causes more pronounced inhibition and prioritizes stress defense, affecting transcriptome and morphology.
In a controlled study, researchers observed that lambs exposed to colder temperatures had increased wool growth, thicker skin, altered physiological traits, and activated specific molecular pathways, highlighting potential targets for enhancing cold tolerance, welfare, and productivity in sheep breeds.
92 citations
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September 2015 in “Journal of Lipid Research” This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.
2 citations
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August 2016 in “Surgery for obesity and related diseases” This study aims to evaluate whether a subset of patients experience undetected hypothyroidism, termed the "famine response," during rapid weight loss after bariatric surgery, which may impact weight loss outcomes. Results are not reported in this abstract.
In this study of Swedish sheep herds, nutritional deficiencies and telogen effluvium, possibly due to cold stress after shearing, were suggested as primary causes of wool loss.
26 citations
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February 2020 in “Frontiers in genetics” This study identified three candidate genes (CORT, FGF5, and CD36) associated with cold climate adaptation in Yanbian cattle through genome resequencing and comparison with African tropical cattle.
3 citations
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January 1988 in “PubMed” This study found that scalp basal cell carcinomas do not appear to behave more aggressively than other types, despite suggestions in the literature.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” This study found that TRPA1-deficient mice exhibited normal cold sensitivity but had decreased mechanical response in nociceptors, suggesting TRPA1's role in mechanotransduction.
10 citations
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April 2022 in “Frontiers in Genetics” This study identified and analyzed 88 MYB genes in Curcuma wenyujin, finding that specific genes are significantly induced by cold, NaCl, and MeJA stress treatments, which suggests their role in stress response mechanisms.
2 citations
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June 2025 in “Cosmetics” This study observed that a five-week topical treatment with cold-pressed Rosa canina seed oil significantly reduced mean wrinkle scores and UV-induced spots in volunteers, suggesting potential anti-aging and photoprotective benefits attributed to its high carotenoid content.
2 citations
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June 1987 in “British Journal of Dermatology” This study demonstrates that warming hands can restore normal blood flow in patients with systemic sclerosis, making their response to cooling similar to that of healthy controls.
October 2023 in “Journal of Family Medicine and Primary Care” This survey in Riyadh Province found that most participants identified malnutrition as the leading cause of iron deficiency anemia and reported symptoms like weakness and cold extremities.
11 citations
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January 1973 in “BMJ” This study reported that cortisone, testosterone, and thyroxine replacement therapy increased energy and hair growth, while decreasing cold sensitivity, in the absence of tumor recurrence.
11 citations
,
January 2020 in “World Journal of Traditional Chinese Medicine” This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.
January 2024 in “Research Square (Research Square)” This study identified key genes related to ischemic stroke through the ferroptosis pathway and highlighted the potential role of specific traditional Chinese medicines in regulating associated biological processes.
February 2024 in “BMC genomics” This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.
3 citations
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June 1987 in “British Journal of Dermatology” In this study, nifedipine provided rapid symptomatic relief in most patients with severe recalcitrant perniosis, but some experienced side effects that limited dosage and two patients were lost to follow-up.
26 citations
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November 2016 in “Current pharmaceutical design” This review examines the potential dermatological benefits of ginseng and ginsenosides, finding no new clinical results but highlighting mechanistic studies on photoaging, wound healing, and skin diseases.
1 citations
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January 2003 in “Current Pharmaceutical Design” This review explores existing research on the therapeutic benefits of ginseng and ginsenosides for various dermatological conditions, but it reports no new clinical results.
1 citations
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July 2021 in “Journal of Skin and Sexually Transmitted Diseases” This review discusses the etiology, clinical features, and treatment options for lipedema and lipedematous scalp and reports no new clinical results.
March 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that faster algorithms for inferring ancestry in genomic data can better capture historical and functional insights into genome variation than traditional methods in large datasets like the UK Biobank.
1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that D-peptide crosslinked MAP hydrogels accelerate skin regeneration and promote adaptive immunity, despite faster scaffold degradation in vivo.
4 citations
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January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified the genes for pyochelin siderophore biosynthesis as a novel target regulated by the heme-responsive PrrH sRNA in Pseudomonas aeruginosa.
2 citations
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November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that metabolic adaptations in skin epithelial stem cells, specifically redox ratio recovery and glycolytic flux modulation, define competitive outcomes between wild-type and mutant cells in different oncogenic environments.
2 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.