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      Wound Healing and Skin Regeneration

      research Wound Healing and Skin Regeneration

      359 citations , January 2015 in “Cold Spring Harbor Perspectives in Medicine”
      This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      Wnt Signaling and Injury Repair

      research Wnt Signaling and Injury Repair

      232 citations , June 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.
      Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

      research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

      96 citations , July 2014 in “Cold Spring Harbor Perspectives in Medicine”
      This review discusses various stem cell compartments in adult murine and human epidermis, examining their expressed markers and characterization assays, and reports no new experimental results.
      Development and Homeostasis of the Skin Epidermis

      research Development and Homeostasis of the Skin Epidermis

      85 citations , July 2012 in “Cold Spring Harbor perspectives in biology”
      This article discusses the roles of epidermal stem cells in maintaining skin homeostasis and highlights how deregulation in signaling pathways may lead to cancer, but it reports no new experimental results.
      Building Epithelial Tissues From Skin Stem Cells

      research Building Epithelial Tissues from Skin Stem Cells

      84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”
      This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
      Diversification and Specialization of Touch Receptors in Skin

      research Diversification and Specialization of Touch Receptors in Skin

      81 citations , June 2014 in “Cold Spring Harbor perspectives in medicine”
      This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.
      Adipocytes in Skin Health and Disease

      research Adipocytes in Skin Health and Disease

      77 citations , March 2014 in “Cold Spring Harbor Perspectives in Medicine”
      This research abstract provides no results, focusing on the equal contributions of the authors in the field of molecular, cellular, and developmental biology from Yale University.
      The Paradox of p53: What, How, and Why?

      research The Paradox of p53: What, How, and Why?

      64 citations , July 2016 in “Cold Spring Harbor Perspectives in Medicine”
      The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

      research Diversity of Fibroblasts and Their Roles in Wound Healing

      58 citations , September 2022 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the heterogeneity of fibroblast subtypes in wound healing and reports no new results; the authors emphasize the potential for diverse fibroblast functions to lead to innovative therapies.
      Lineage Analysis of Epidermal Stem Cells

      research Lineage Analysis of Epidermal Stem Cells

      57 citations , January 2014 in “Cold Spring Harbor Perspectives in Medicine”
      Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
      An Overview of Alopecias

      research An Overview of Alopecias

      53 citations , March 2014 in “Cold Spring Harbor Perspectives in Medicine”
      The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
      Epidermal Polarity Genes in Health and Disease

      research Epidermal Polarity Genes in Health and Disease

      32 citations , December 2014 in “Cold Spring Harbor Perspectives in Medicine”
      This article reviews the role of polarity proteins in epidermal morphogenesis and homeostasis and discusses how their alteration may contribute to skin disease, but reports no new experimental findings.

      research Plasticity of Epithelial Cells during Skin Wound Healing

      31 citations , November 2022 in “Cold Spring Harbor Perspectives in Biology”
      This review explores how epithelial cells from various niches in the skin respond and adapt during acute wound repair, highlighting the role of cellular plasticity in reepithelialization and restoring the skin's barrier function.
      The Genetics of Human Skin Disease

      research The Genetics of Human Skin Disease

      24 citations , October 2014 in “Cold Spring Harbor Perspectives in Medicine”
      Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
      Building and Maintaining the Skin

      research Building and Maintaining the Skin

      22 citations , October 2021 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.
      Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy

      research Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy

      10 citations , November 2019 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.
      The Wound Microbiome

      research The Wound Microbiome

      8 citations , October 2022 in “Cold Spring Harbor perspectives in biology”
      The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

      research Bioinspired Strategies for Wound Regeneration

      6 citations , December 2022 in “Cold Spring Harbor Perspectives in Biology”
      This review examines diverse regenerative strategies in animals and highlights how biochemical, immunological, and mechanical signals can work together for successful skin regeneration in adult mammals, but it reports no new experimental results.