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This study found that extracellular vesicles derived from 3D cultures of cervical cancer cells have small RNA profiles more similar to those in patient plasma than those from 2D cultures.

In this study, researchers identified over 250 new genetic loci linked to severe male pattern baldness, and developed a prediction algorithm that could accurately differentiate between those with severe and no hair loss.

This study presents an improved reference genome for the African spiny mouse, which may aid in understanding its tissue regeneration at the molecular level.

This study identified the genes for pyochelin siderophore biosynthesis as a novel target regulated by the heme-responsive PrrH sRNA in Pseudomonas aeruginosa.

This study found that epidermal stem cells in live mice exhibit coordinated intercellular Ca 2+ signaling governed by G2 cycling stem cells and mediated by Connexin43, essential for tissue-wide communication during regeneration.

This study suggests that BLMP-1 is important for timely molting and oscillatory gene expression in C. elegans, indicating a potentially conserved mechanism for rhythmic skin regeneration.

This review found that common post-acute COVID-19 symptoms include fatigue, dyspnea, insomnia, and anxiety, indicating they can persist beyond 60 days after initial infection.

This study developed the iCOUNT tool, which provides insights into stem cell behavior by tracking cell division events and molecular consequences in human and mouse neural stem/progenitor cells.

This study found that in Alcorcón, Spain, migrants from Sub-Saharan Africa, the Caribbean, and Latin-America had a higher risk of COVID-19 infection during the first wave compared to Spaniards.

This study estimates that approximately 230,000 tactile afferent fibers innervate the human body's skin, with varying densities across different regions correlating with spatial acuity and hair follicle density.

This case-control study from Lombardy, Italy, observed that men over 55 taking 5-alpha reductase inhibitors for benign prostatic hyperplasia were hospitalized for COVID-19 at a lower rate than age-matched controls, suggesting potential protective effects against severe disease.

This study introduced Neurospectrum, a framework that effectively identifies meaningful neural dynamics by encoding neural activity into latent trajectories, and reported that it outperformed traditional methods in tracking synchronization, reconstructing stimuli, and identifying fMRI biomarkers in various datasets.

This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.

This study introduces scINSIGHT, a method to analyze single-cell RNA sequencing data that outperforms existing techniques in identifying gene expression patterns across different biological conditions.

This study used scRNA-Seq to map the transcriptional changes during zebrafish hair cell regeneration, revealing distinct phases including injury response, transient regeneration gene activation, and reactivation of developmental programs.

This study presents a new method using primary human lung tissue cells to rapidly identify viral entry factors and therapeutics for SARS-CoV-2, revealing compounds overlooked by conventional screening systems.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This study suggests that platelet-rich plasma may improve pain and function in patients with partial-thickness rotator cuff tears and tendinopathy short-term, but the long-term benefits are unclear.

In this study, researchers found that inhibiting YAP signaling in skin wounds leads to regenerative repair with active Trps1 and Wnt signaling, contrasting the typical fibrotic scarring process.

This study found that the DNN-DTIs prediction model achieved high accuracy in predicting drug-target interactions, suggesting its potential application in drug repositioning and the discovery of new uses for existing drugs.

In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.

In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.

This study found that host androgens like testosterone promote Staphylococcus aureus pathogenesis and skin infections by activating the agr quorum sensing system, revealing a mechanism for sex-dependent differences in these infections.

This study found that RANKL promotes the regeneration of type II alveolar epithelial cells in lung tissue, suggesting it may play a role in lung repair processes for diseases like COPD and fibrosis.

This study investigated various animal tissues from adult mice and embryonic chicks, finding that tissue stiffness follows a sub-linear power law relationship with Collagen-I levels, consistent with cellularized collagen gels but not acellular ones.

This study observed that both SARS-CoV-2 and other acute respiratory infections are linked to a wide range of long-term symptoms, highlighting the need to investigate post-acute sequelae beyond COVID-19.

This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.

This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

In this study, overexpression of miR-29 in mice led to aging-related phenotypes and early lethality, demonstrating its significant role in driving aging processes.

This study found that metabolic adaptations in skin epithelial stem cells, specifically redox ratio recovery and glycolytic flux modulation, define competitive outcomes between wild-type and mutant cells in different oncogenic environments.