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This research found that Foxc1 transcription factor and COL17A1 are critical in regulating quiescence and hair thinning in hair follicle stem cells, with aging-related DNA damage leading to hair loss.

This study indicates that COL17A1 plays a crucial role in the differentiation process of hair-follicle-associated pluripotent stem cells.

The study found that aging in hair follicle stem cells leads to hair follicle miniaturization and eventual hair loss in both wild-type mice and humans by proteolyzing type XVII collagen.

Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.

This study investigated the gene Col19a1, finding its expression is specific to certain cells during hair follicle development in mice, suggesting its potential role in hair follicle morphogenesis.

This case study suggests that obstructive sleep apnea syndrome may be hereditary in patients with connective tissue disorders due to a variant in the COL1A2 gene.

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

This review discusses the role of Foxc1 and type XVII collagen in hair follicle stem cell quiescence and aging, identifying mechanisms that relate to hair thinning and hair loss, and reports no new results.

This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.

This study found that ginseng-derived nanoparticles promoted skin cell proliferation and facilitated wound healing in a mouse model.

In this laboratory study, ASC-conditioned medium showed higher therapeutic potential than extracellular vesicles alone in reducing inflammation and catabolic activity in human chondrocytes with an osteoarthritis phenotype, highlighting its possible use in osteoarthritis management.

This study reports identifying 12 candidate genes potentially involved in regulating hair follicle development in cashmere goats, which could contribute to improving cashmere production.

This study identified several candidate genes related to wool production traits and adaptation to hot, arid environments in Iranian sheep, highlighting potential targets for future inbreeding programs.

This review outlines the genetic basis of GABEB, highlighting reduced type XVII collagen as a distinguishing marker from Herlitz JEB, and discusses potential therapeutic avenues without presenting new results.

This review discusses recent findings on the mechanisms driving bullous pemphigoid, highlighting epitope spreading and the roles of regulatory T cells, and reports no new experimental results.

This study found that dermal sheath stem cell characteristics are lost with aging in humans, affecting skin rejuvenation and structure, and identified specific proteins like Activin A influencing keratinocyte and fibroblast activity.

This study found that SIRT1 negatively regulates fibroblast activation and excessive scar formation, suggesting it may be a promising drug target for treating hypertrophic scars.

This study identified novel biomarkers through gene expression differences between keratinocytes and fibroblasts in newborn mice, which may aid in developing therapies for skin conditions.

This study found that TGF-β2 may enhance collagen expression and spheroid formation in human dermal papilla cells, which could improve their hair inductivity and maintenance.

This review discusses the role of collagen XVII in maintaining stem cell niches and its impact on skin aging and wound repair, without reporting new clinical results.

This study observed increased proliferation and certain gene expressions in dermal papilla cells exposed to an 808 nm laser diode array at doses above 0.5 J/cm².

This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.

This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.

This article discusses junctional epidermolysis bullosa caused by COL17 deficiency, noting a lack of experimental therapies and the impact of nonsense mutations, but it reports no new clinical results.

Focal palmoplantar callosities may help diagnose non-Herlitz junctional epidermolysis bullosa.

This study identified 417 genes with differential expression at varying stages of cashmere growth in goats, highlighting their potential role in tissue remodeling and cashmere regeneration.

This study compared the effectiveness of different thread types in improving collagen profiles in UVB-exposed aging model rats, finding that PCL threads were more effective than PDO and PLLA in enhancing dermal collagen characteristics.

This study suggests that the CXCL8 gene may regulate cashmere fineness in Liaoning cashmere goats, providing new insights into the cellular mechanisms of cashmere growth and quality.

This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.