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Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

SHBG may be a useful early indicator and treatment target for PCOS.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Certain skin conditions may indicate or increase the risk of Parkinson's disease.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.