research Summary of Findings on Psychotropic Medications
Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
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research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Progesterone Enhances Ethanol-Induced Modulation of Mesocortical Dopamine Neurons: Antagonism by Finasteride
Progesterone boosts alcohol's effect on brain, finasteride counters it.
research Post-Finasteride Syndrome: An Emerging Clinical Problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Examining the Relationship Between Alopecia Areata, Androgenetic Alopecia, and Emotional Intelligence
Alopecia patients struggle with emotions and stress, and improving emotional intelligence may help manage hair loss.
research A Double-Blind, Placebo-Controlled Study of Inositol in Trichotillomania
Inositol was not more effective than a placebo in treating trichotillomania.
research Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
research Nocebo Effect in Dermatology
Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
research Post-Finasteride Syndrome – Does It Really Exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research Long-Term Effects of Chemotherapy in Children With Cancer
Chemotherapy in children often causes hair loss, nausea, vomiting, and mood swings.
research New Challenge to Cancer and Longevity
A group has developed therapies that show promise for treating cancer and various other conditions.
research Genetic Defects of Female Sexual Differentiation
Genetic mutations can affect female sexual development, requiring personalized medical care.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects
Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.
research DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Congenital Adrenal Hyperplasia: Current Insights in Pathophysiology, Diagnostics, and Management
Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Ancient-Modern Concordance in Ayurvedic Plants: Some Examples
Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
research Hormesis And Medicine: Biphasic Dose-Response Relationship
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Association of Suicidality and Depression With 5α-Reductase Inhibitors
Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.