May 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” High doses of rosemary extract can harm the liver, kidneys, and reproductive organs in young rats.
May 2023 in “Clinical and translational neuroscience” Tailored neurorehabilitation programs improve life quality for post-COVID-19 patients.
The study concludes that long COVID recovery involves time, various treatments, and a strong patient-provider relationship.
March 2023 in “Translational Andrology and Urology” 5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
January 2023 in “Food and nutrition sciences” Most people using the supplement Renew saw health improvements, especially in sleep and energy, faster than with regular vitamins.
January 2023 in “Revista Da Associacao Medica Brasileira” The document concludes that women's health needs a holistic approach, considering all life stages, promoting lifestyle changes, regular exercise, proper diet, and vaccinations, with health professionals playing a key role in education and guidance.
December 2022 in “Journal of neurodevelopmental disorders” Hair follicle sampling is a practical method for measuring biomarkers in children with and without Fragile X syndrome.
September 2022 in “Dermato” Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.
June 2022 in “Frontiers in Medicine” Acupuncture and moxibustion may help treat hair loss, but more research is needed.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
April 2018 in “Gynäkologische Endokrinologie” Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
A 14-year-old girl with a condition that makes her hair easy to pull out also has a hair-pulling disorder, and treatment helped but she relapsed after a year.
December 2022 in “JAMA network open” 5α-Reductase inhibitors may increase depression risk but not dementia or suicide.
January 2010 in “Yearbook of Endocrinology” Older men with lower levels of available testosterone are more likely to be frail.
228 citations,
February 2003 in “Urology” Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.
37 citations,
February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
7 citations,
January 2003 in “Elsevier eBooks” Testosterone is crucial for development, growth, and various body functions in mammals.
January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
414 citations,
August 2005 in “Nature” Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
215 citations,
November 2000 in “Journal of Investigative Dermatology” The study demonstrated the use of tetracycline-regulated transactivators (tTA and rTA) linked to the keratin 5 promoter to achieve conditional gene expression in the epidermis of transgenic mice. By modulating doxycycline levels, researchers could control β-galactosidase activity, with significant increases observed in the epidermis, particularly in hair follicles and the basal layer. The K5/tTA line showed a 500-fold increase in enzyme activity without doxycycline, while K5/rTA lines exhibited a 3- to 50-fold increase with doxycycline induction. This system allowed for precise temporal and quantitative control of gene expression, proving useful for studying epidermal biology, including growth control, differentiation, carcinogenesis, and wound healing. The findings suggested that the K5 promoter might be more effective than the CMV promoter for maintaining expression in keratinocytes.
194 citations,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
4 citations,
July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
2 citations,
November 2020 in “Fertility Research and Practice” The survey helps identify menstrual irregularities and excess male hormones, aiming to detect conditions like Polycystic Ovary Syndrome.
Ziziphus jujuba and Eclipta alba leaf extracts improve blood sugar levels and cognitive function in diabetic rats.
December 2023 in “Expert Opinion on Drug Safety” Finasteride use is linked to increased reports of cognitive problems, especially in younger people with hair loss.
November 2022 in “Journal of Investigative Dermatology” COVID-19 patients with hair loss experienced greater cognitive deficits and more symptoms of depression, anxiety, and stress.
COVID-19 patients with hair loss experienced more cognitive issues and these issues were linked to higher levels of depression, anxiety, and stress.
Controlling Tslp can improve health in AEC syndrome patients.
51 citations,
November 2005 in “Journal of Medical Primatology” Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.