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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

High BMI worsens hair growth in women with PCOS.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

New cancer treatments aim to reduce side effects and improve effectiveness.

Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Growth factors are crucial for hair development and could help treat hair diseases.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

The hair tonic from Usada Bali plants increased hair growth without irritating the skin.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.

Finasteride doesn't affect erections much, but may decrease libido in men.

Psychotropic drugs can help treat skin conditions affected by mental health, but dermatologists must use them carefully due to side effects and patient concerns.

Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.