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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Hair loss needs more research for better treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

CDP is crucial for lung and hair follicle cell development.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

K6hf is a unique protein found only in a specific layer of hair follicles.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.