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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Certain DNA variants can predict straight hair in Europeans but are not highly specific.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.