2 citations
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April 2023 in “South East European Journal of Immunology” This pilot study found elevated levels of leptin and other proinflammatory molecules in the serum of melanoma patients, suggesting a potential role for leptin in melanoma progression and a possibility for targeting it in adjuvant therapy.
2 citations
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January 2023 in “International journal of biological sciences” This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.
1 citations
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May 2025 in “The Journal of Phytopharmacology” This review identifies natural plants that possess androgen-related compounds, highlighting the potential of phytoandrogens as alternatives to allopathic treatments for conditions like hypogonadism, impotence, infertility, and erectile dysfunction.
1 citations
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May 2025 in “Scientific Reports” In this study, researchers found no significant differences in serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology linked to the condition.
1 citations
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March 2024 in “Signal transduction and targeted therapy” In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.
1 citations
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April 2021 in “Current Stem Cell Reports” This review discusses the role of metabolism in maintaining adult stem cell homeostasis with aging and highlights the potential benefits of dietary restrictions on stem cell function and longevity. It reports no new clinical results and emphasizes the need for further molecular studies.
1 citations
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March 2021 in “Dermatological reviews” This review discusses recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia in males, females, and children, but reports no new clinical results.
1 citations
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October 2017 in “Elsevier eBooks” This review examines the effects of antiandrogens on female reproductive systems, particularly regarding environmental endocrine disruptors, and presents no new research findings.
1 citations
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May 2017 in “InTech eBooks” This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.
1 citations
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January 2009 in “Trepo - Institutional Repository of Tampere University” This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.
May 2026 in “Frontiers in Cell and Developmental Biology” In this study, researchers suggest that hair follicle miniaturization in conditions like androgenetic alopecia may result from impaired conversion of quiescent stem cells to progenitor cells, influenced by the follicular niche, its collagen network, and various mechanical constraints.
April 2026 in “Frontiers in Cell and Developmental Biology” This review summarizes the role of G-protein-coupled receptors in wound healing and reports no new clinical results, highlighting their importance in signaling pathways and recent discoveries in their functions.
January 2026 in “MEDS Clinical Medicine” This review discusses the combined use of plum-blossom and Daoma needle therapy for androgenic alopecia, emphasizing its potential benefits and the need for further clinical research, but reports no new results.
This study discusses the potential of phytochemicals, such as isoflavones and polyphenols, to manage PCOS symptoms by improving insulin resistance, regulating hormones, and reducing cyst size, highlighting their promise as alternative treatments given the limitations of current pharmacological options.
December 2025 in “Scientific Reports” In this study, cedrol was found to reduce lipid accumulation in the liver and adipose tissues of dexamethasone-treated mice by antagonizing glucocorticoid receptors, suggesting its potential utility in treating dexamethasone-induced lipid metabolism disorders.
In this study, researchers found no significant differences in the serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology is associated with this condition.
October 2024 in “Frontiers in Oncology” This review examines the potential of K18 as a diagnostic and prognostic marker in epithelial-derived tumors, highlighting its specific expression in tumor tissues and interaction with proteins involved in tumor progression, without reporting new clinical findings.
April 2024 in “Nepal journal of dermatology, venereology & leprology” This review highlights that vitamin D is increasingly recognized for its roles in skin health, including treatment of psoriasis, potential applications in conditions like atopic dermatitis, and possible prevention of skin malignancies, as observed in various studies linking low levels to autoimmune skin diseases.
December 2023 in “Journal of the Endocrine Society” In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.
In this study, a very low-calorie ketogenic diet significantly improved metabolic and hormonal profiles in obese men, but did not significantly enhance most semen parameters except for sperm motility.
September 2021 in “International Journal of Biomedicine” This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.
December 2018 in “IntechOpen eBooks” This review discusses recent advancements in understanding neuroendocrine regulation of keratin biology and highlights the potential of neurohormones to treat skin disorders, but it reports no new clinical results.
October 2018 in “InTech eBooks” This research suggests that mouse mutants and genomics can help study hair biology and epithelial differentiation by focusing on the role of the Foxn1 gene.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
February 2010 in “ePrints Soton (University of Southampton)” This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
January 2006 in “Advances in developmental biology” This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.
70 citations
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August 2006 in “Cancer Research” This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.
52 citations
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July 2001 in “Molecular and cellular endocrinology” This study found that activin A significantly enhances wound healing by stimulating granulation tissue formation and re-epithelialization in mice, and suggests potential in developing treatments for stroke and brain trauma.