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The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Vitamin D receptor is crucial for skin wound healing.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Targeting NCoR1 can help treat heart enlargement and dysfunction.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Human keratinocytes do not naturally respond to androgens.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.