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In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.

This review discusses the potential link between androgenic alopecia, androgens, and the severity of COVID-19, highlighting possible therapeutic targets but reports no new clinical results.

In this study, eight patients with hereditary vitamin D-resistant rickets who share a specific VDR mutation showed improved clinical symptoms except alopecia after up to 11 years of treatment.

This review discusses the complex role of Runx family genes in regulating stem cells in blood and skin tissues and reports no new experimental results.

This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

In this study, researchers found that shorter CA repeats in the ERbeta gene are correlated with PSA expression, and PSA immunoexpression is associated with increased disease-free survival in breast cancer.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This study found that extract of Hura crepitans inhibited androgen-accelerated NT-4 activity and ameliorated the retardation of hair regrowth in dihydrotestosterone-implanted mice, suggesting a potential role for NT-4 inhibitors in AGA.

This study found that NKIRAS2 expression affects skin tumor suppression and HRAS-driven transformation in mice, indicating its role in carcinogenesis depends on expression level and cellular context.

This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.

This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.

This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.

This paper provides a comprehensive review of melanocytes' roles in skin biology, focusing on their pigmentation and immune functions, and suggests potential research opportunities for preventing and treating skin disorders.

In a rat model of benign prostatic hyperplasia, this study found that purple corn extract may improve symptoms by inhibiting prostate enlargement, reducing androgen receptor signaling, and exerting anti-inflammatory effects.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

In this research, the authors identify coordinated mechanical forces as crucial for hair follicle development in mammals, with contractile, proliferative, and proteolytic activities facilitating the formation and sectioning of epithelial structures crucial for forming a functional tissue.

This review highlights the potential of targeting hepatic stellate cell ferroptosis as a treatment strategy for liver fibrosis, underscoring the need for further research into ferroptosis mechanisms in these cells to better understand and combat this condition.

Balding men have harder scalps.

This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.

This review discusses the potential of adipose-derived stem cells for regenerative medicine, highlighting their ability to differentiate, secrete factors, and modulate the immune response, but reports no new findings.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.

This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.

In this study on testosterone-induced benign prostatic hyperplasia in rats, hydroxychloroquine significantly reduced prostate-related markers and enhanced therapeutic effects when combined with finasteride, suggesting potential as a new treatment approach.

This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.

The study emphasizes that telomere shortening is identified as the sole cause of aging among the twelve hallmarks and suggests that increasing telomere and rDNA array length in adult stem cells might effectively reverse aging and extend lifespan.

This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.

This study identified significant trends in interest around selective androgen receptor modulators, with increasing attention contrasting stagnant or declining interest in post-cycle therapies and anabolic steroids, and calls for clinicians to use social and prescription data to adjust treatment protocols accordingly.

In this review, the authors explored how epigenetic regulation influences the development of plant trichomes, highlighting the significant role of microRNA-mediated post-transcriptional regulation and suggesting new research avenues in plant epigenetics.