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A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Spironolactone does not increase the risk of breast cancer recurrence.

Neuropsychiatric lupus is a severe form of lupus that needs strong treatment to improve life quality.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

Teriflunomide is effective and generally safe for treating relapsing multiple sclerosis, reducing relapse rates and disability progression.

Up to half of adult women may experience hair loss, and doctors should use medical history, exams, and tests to find the cause and treat it.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Nerves are crucial for the regeneration of various body parts in many animals.

Knowing about finasteride's sexual side effects increases reported dysfunction.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.