March 2019 in “Chinese Journal of Dermatology” This review discusses the factors involved in androgenetic alopecia, emphasizing genetic susceptibility as a key contributor and detailing how follicle miniaturization completes the condition's development; it reports no new clinical results.
September 2018 in “Chinese Journal of Dermatology” This study found that angiogenin can inhibit the expression of type Ⅰ collagen and fibronectin in dermal papilla cells from androgenetic alopecia areas in vitro by affecting TGF-β1 and its signaling pathway.
October 2017 in “Chinese Journal of Dermatology” October 2017 in “Chinese Journal of Dermatology” May 2017 in “Chinese Journal of Dermatology” This study reported that alopecia can moderately impact patients' quality of life and is linked to a depressive tendency, with frequent medical visits and higher quality of life impairment as risk factors.
July 2016 in “Chinese Journal of Dermatology” This study found that low-level laser therapy increased hair density in men with androgenetic alopecia, with even greater improvements seen when combined with finasteride.
In this study, the authors reported that certain SNPs on chromosome 20 were associated with androgenetic alopecia in the ethnic Han population of Yunnan, with specific alleles linked to higher likelihood of developing the condition.
September 2014 in “Chinese Journal of Dermatology” In this study, several dermoscopic features such as hair diameter diversity, brown peripilar sign, and focal atrichia were frequently observed in both male and female androgenetic alopecia patients, highlighting these as potential AGA indicators.
July 2014 in “International Journal of Dermatology and Venereology” This review discusses how androgens and cytokines may interact in androgenetic alopecia and reports no new results; the authors note the need for further research.
September 2013 in “International Journal of Dermatology and Venereology” This article reviews the challenges in effectively treating androgenic alopecia and reports no new clinical results, emphasizing its impact on patients' appearance and mental health.
July 2013 in “International Journal of Dermatology and Venereology” This study found that the ZMY-1 hair transplantation system significantly reduced the time needed to make holes in hair-transplant surgery compared to manual punching, while maintaining similar safety and tissue survival rates.
May 2012 in “International Journal of Dermatology and Venereology” This article reviews definitions, classifications, and treatments for female pattern hair loss, including newer therapies like adenosine and phototherapy, but reports no new clinical findings.
June 2010 in “Chin J Postgrad Med” In this study, prednisone and zinc preparation combined with 2% minoxidil significantly improved curative rates for androgenetic alopecia after 9 to 12 months compared to prednisone and zinc preparation alone.
January 2010 in “International Journal of Dermatology and Venereology” This review discusses the relationship between dermal papilla cells and androgenetic alopecia, noting the involvement of androgens and mental factors, but reports no new clinical results.
2 citations
,
January 2025 in “Pharmaceutical Research” This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.
69 citations
,
February 2021 in “PLoS Computational Biology” This study found that securinine and ajmaline significantly inhibited hepatocellular carcinoma cell viability and induced apoptosis, with securinine showing lower toxicity to normal liver cells.
65 citations
,
September 2010 in “Journal of the Neurological Sciences” This article discusses Kennedy's disease, detailing its genetic cause, symptoms, and diagnostic criteria, but reports no new clinical findings and highlights a lack of causal therapy.
61 citations
,
May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
50 citations
,
July 2014 in “International Journal of Clinical Pharmacology and Therapeutics” This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.
38 citations
,
February 2005 in “The journal of sexual medicine” This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.
33 citations
,
November 2008 in “European Journal of Pharmaceutical Sciences” This study found that St. John's wort treatment for two weeks induced finasteride metabolism and reduced its plasma exposure in healthy men.
27 citations
,
April 2017 in “British Journal of Dermatology” This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.
25 citations
,
February 1989 in “The Journal of Clinical Pharmacology” This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
18 citations
,
May 2014 in “Menopause” This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.
14 citations
,
February 1994 in “Tetrahedron Letters” This study found that using anhydrous cerium(III) chloride with alkyl Grignard reagents significantly improved the addition to sterically hindered 17-ketosteroids, resulting in high yields and stereoselectivity.
13 citations
,
November 2014 in “Toxicology Letters” This study found that finasteride selectively inhibited UGT1A4 in vitro but is unlikely to cause clinically significant drug interactions mediated through hepatic UGT enzymes in vivo.
10 citations
,
October 2009 in “Clinical Therapeutics” This study found that the orally disintegrating tablet and standard tablet formulations of finasteride met bioequivalence criteria in fasting healthy adult male Han Chinese volunteers, although there was a significant difference in time to maximum concentration.
9 citations
,
August 2013 in “PLOS ONE” This study validated that the 20p11 genetic locus is associated with increased risk of androgenic alopecia in the Chinese Han population, suggesting shared genetic factors between Chinese and European populations.
8 citations
,
January 2018 in “PubMed” The study reported that reducing finasteride particle size significantly improved its cellular permeation through prostate epithelial cells, though it had a lesser impact on systemic pharmacokinetics and tissue distribution in rats.
8 citations
,
February 2014 in “General and Comparative Endocrinology” In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.