January 2026 in “Journal of Epidemiology” This cross-sectional study reported that adults with greater hair loss severity had significantly higher odds of hypertension, diabetes, and cardiometabolic multimorbidity, suggesting a possible link between hair loss and cardiometabolic health.
November 2025 in “Journal of Laboratory Medicine” This study found that cortisol levels, a biomarker of chronic stress, significantly increased in the post-COVID-19 lockdown period compared to pre-lockdown and during-lockdown periods, especially among females and young adults, reflecting sustained psychological stress from the pandemic.
January 2024 in “Scientific reports” This study found that undiluted mint leaf extract effectively inhibited multidrug-resistant Staphylococcus aureus and killed Culex pipiens larvae, suggesting its potential as a biocontrol strategy around hospitals.
December 2022 in “Research Square (Research Square)” In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.
3 citations
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October 2024 in “Frontiers in Medicine” This study investigated single-cell changes in photoaged skin, revealing distinct cell clusters and increased activity in PD-L1 and PD-1 pathways in sun-exposed areas, enhancing understanding of UVA-induced skin damage and potential prevention targets for photoaging and UV-induced skin cancers.
36 citations
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January 2021 in “Scientific Reports” This study identified key genes and signaling pathways involved in the growth phases of Pashmina goat hair follicles, highlighting the role of several gene families and transcription factors in fiber quality and growth regulation.
11 citations
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October 2020 in “Plant biotechnology journal” This study found that manipulating SIMK expression in alfalfa affects root hair growth, infection thread and nodule formation, and overall plant biomass, highlighting its potential biotechnological applications.
March 2026 in “Dermatology and Therapy” This study identified distinct plasma miRNA profiles in alopecia areata that may aid in diagnosis and therapy, but further validation is needed to confirm these exploratory findings.
This study found that 62 plasma proteins are significantly associated with the risk of obstructive sleep apnea, offering potential targets for new therapeutic strategies.
7 citations
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December 2020 in “Pharmaceutics” In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.
February 2024 in “Skin research and technology” The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.
24 citations
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April 2016 in “Experimental Dermatology” This study found that chemical treatments like perming, dyeing, and bleaching significantly alter amino acids and lipids in human hair, which may impact hair strength and quality.
June 2026 in “Frontiers in Medicine” This registry-based analysis observed rapid growth in hair-loss clinical trials between 2015 and 2025, highlighting regional concentration, prevalent therapeutic categories, and diverse outcome reporting while emphasizing the need for standardization and broader representation.
This study analyzed hair-loss clinical trials from 2015 to 2025 and found that, while the number of registrations increased globally, research activity was concentrated in certain regions and varied in therapeutic approaches and outcome specifications.
May 2026 in “Stem Cell Research & Therapy” In this study, researchers identified KRT6A as a potentially important gene in mesenchymal stem cell-derived treatments for alopecia areata, revealing its role as a diagnostic marker, predictor of disease severity, and a protective factor, with overexpression alleviating hair loss in experimental models.
April 2026 in “Therapeutic Advances in Drug Safety” This study developed a new clustering model to improve detection of drug-induced cognitive disorder risk signals, finding that it identified drugs with moderate risk signals, like Carbidopa/Levodopa, missed by traditional methods, enhancing clinical assessment comprehensiveness.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
June 2025 in “Microorganisms” In this study, researchers observed significant differences in hair follicle microbiome diversity and microbial composition between hair loss and healthy groups, uncovering specific patterns and functional changes associated with female pattern hair loss, which may aid future targeted approaches for androgenetic alopecia.
This article reviews how to properly take a dermatological history and conduct physical examinations for skin rashes and malignancies, discussing commonly used diagnostic tools and the Dermatology Life Quality Index system.
29 citations
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June 2018 in “Scientific Reports” In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
14 citations
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October 2018 in “PloS one” In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.
6 citations
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May 2020 in “Scientific reports” In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.
5 citations
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September 2021 in “Frontiers in Cell and Developmental Biology” This study found that 3D-cultured dermal papilla cells more accurately mimic in vivo conditions compared to 2D cultures, enhancing our understanding of molecular mechanisms in androgen-induced alopecia.
2 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the culture conditions, not species-specific differences, determined whether sika deer dermal papilla cells adopted a 3D spheroidal or 2D monolayer growth pattern, influencing their hair-inducing ability.
1 citations
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November 2024 in “Orphanet Journal of Rare Diseases” Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.
March 2026 in “Pharmaceuticals” This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.
July 2025 in “Food Safety and Health” This study used metabolomics to identify distinctive metabolic and phenolic profiles in American ginseng (Panax quinquefolius) from various regions, revealing specific biomarkers that can help differentiate between ginseng from Northeast China, Shandong, and the United States.
December 2023 in “Animal research and one health” This study investigated circRNA expression in Zhongwei goat skin at different growth stages and found that certain circRNAs, such as circRNA8782 and circRNA3173, may play roles in regulating wool curvature by affecting signaling pathways and fibroblast proliferation.
This study explored the molecular communication between hair matrix cells and dermal papilla cells in cashmere goats, revealing key ligand-receptor pairs and signaling pathways that facilitate intercellular crosstalk and potentially influence hair growth mechanisms.
This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.