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New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.

Hair diseases can have psychological effects and should be treated with a combination of psychosomatic care, therapy, and medication.

Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

The four main causes of hair loss in children are fungal infections, pulling out hair, autoimmune hair loss, and stress-related hair shedding.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.

Finasteride use can cause depression-like behavior in male rats.

Metformin helped improve the quality of life for Chinese women with PCOS, especially in physical health and symptoms like infertility, acne, and hair loss.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

High levels of the seizure medication sodium valproate can cause hair loss.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Platelet-Rich Plasma (PRP), a substance from a patient's own blood, can stimulate hair regrowth in people with Androgenetic Alopecia (AGA) who haven't had success with other treatments, but more research is needed to optimize its use.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

The document suggests that there might be an autoimmune link between polycystic ovary syndrome and Graves' disease.