research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
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research Effects of Oral Contraceptives on the Quality of Life of Women with Polycystic Ovary Syndrome: A Crossover Randomized Controlled Trial
Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.
research The Association Between Serum Ferritin and 25-Hydroxyvitamin D and Metabolic Syndrome in Korean Women: The Korea National Health and Nutrition Examination Survey 2010–2012
Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.
research The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia
Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
research Unlocking the Potential of the Secretome in Hair Growth Enhancement
Secretome-based therapies could improve hair growth better than current treatments.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research A Systematic Review of Antiandrogens and Feminization in Transgender Women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant did not significantly improve hair growth in men with hair loss.
research Treating Alopecia Areata: Current Practices Versus New Directions
New treatments like JAK inhibitors show promise for reversing alopecia areata.
research Preliminary Investigation on Microneedling with Low-Level LED Therapy and Growth Factors in Hair Loss Related to COVID-19
The treatment might help COVID-19 related hair loss, but more research is needed.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research DC-HIL+ Myeloid-Derived Suppressor Cells Are Elevated in the Peripheral Blood and Lesional Skin of Cutaneous Lupus Patients
Cutaneous lupus patients have higher levels of certain immune cells in their blood and skin.
research Oral Dysbiosis in Palmoplantar Pustulosis Patients with Arthro-Osteosis
People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.
research A First-In-Human Study of BLZ-100 (Tozuleristide) Demonstrates Tolerability and Fluorescence Contrast in Skin Cancer
BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
research Urethral PSA Production After Radical Prostatectomy
After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.
research The Efficacy of 1550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia
Finasteride helps female-pattern hair loss.
research Pooled Safety and Tolerability Data from Four Placebo-Controlled Teriflunomide Studies and Extensions
Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research 5-Alpha-Reductase Inhibitors for Prostate Cancer Chemoprevention: An Updated Cochrane Systematic Review
5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
research The Nocebo Effect: A Clinician's Guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
research Increased Lactate Dehydrogenase Activity Is Dispensable in Squamous Carcinoma Cells of Origin
High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
research Negative Pressure Wound Therapy Augmented Full-Thickness Free Skin Grafting in Cats: Outcome in 10 Grafts Transferred to Six Cats
Negative pressure wound therapy is effective for skin grafts in cats.
research Regenerative Surgery in the Management of Leg Ulcers
Using a patient's own tissue for micro-grafts may effectively treat non-healing leg ulcers and relieve pain.
research Fat Transfer for the Management of Soft Tissue Trauma: The Do's and Don'ts
Fat transfer can be effective for soft tissue trauma if the patient is chosen carefully and the procedure is done correctly.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research The Relationship Between the Expression of Cytokeratin 5/6 and Clinicopathologic Factors in Invasive Breast Carcinoma
CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.
research Activation of Breast Cancer Cell Proliferation by ROR-Alpha Through Aromatase Promoter
ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.
research Inhibin A Is Downregulated During Chemotherapy in Patients With Breast Cancer
Chemotherapy significantly lowers Inhibin A levels in breast cancer patients.
research Alopecia Areata: Treatment Options and Efficacy
Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.