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Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Lower irisin levels in the blood may indicate more severe acne.

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

Surgical hair restoration involves moving hair from a non-balding area to a balding area, with the transplanted hair not subject to male pattern baldness. Medications can slow hair loss and regrow some hair, but successful treatment needs careful planning, skill, and ethical responsibility due to progressive hair loss and limited donor hair.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

Scalp reduction can improve hair distribution in certain baldness cases but requires careful patient selection and understanding of facial structure.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

Minoxidil helps hair cells live longer and grow longer.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Cosmetic treatments like bleaching and perming can greatly reduce opiate levels in hair, possibly leading to false-negative drug tests.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.