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Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Skin issues can indicate immune system problems.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Coconut oil makes hair stronger and more flexible than mineral oil.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Many research paper titles in dermatology journals lack scientific precision.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.